Both titles deal with the discovery and role of endorphinsnaturally occurring opiates in the brainbut treat the material differently. Goldberg presents a very readable account of the discovery of endorphins, beginning with research on pig brains in the early 1970s and ending a decade later as endorphins are being considered for use in such diverse areas as obstetrics, phantom limb pain, and schizophrenia. He offers many references to actual dates, individuals, and places. Levinthal's more scholarly treatise presents a well-documented historical overview of opium and the structure, function, and chemistry of the brain. After briefly discussing the discovery of endorphins, he focuses on the various applications and parallels of endorphins to mental and physical conditions. While both titles are of great interest, Levinthal's represents the more complete and comprehensive treatment of the subject. Barbara J. Powell, Veterans Administration Medical Ctr., Kansas City, Mo.