Metabolism at a Glance (Blackwell At a Glance Series) / Edition 2 available in Paperback
Using the familiar At A Glance format, the second edition of this best-seller takes the reader through a complete review course of metabolism in health and disease. The salient features of a metabolic pathway are highlighted on a detailed background map, offering the choice to absorb as much, or as little, of the available information as required.
The text has been updated to include inborn errors of metabolism and new chapters on porphyrins, cholesterol and sports/exercise metabolism. Another major feature is the extensively revised chapters on diabetes.
Metabolism At A Glance will be an invaluable aid to students requiring a knowledge of metabolism for undergraduate medical, biochemistry, veterinary, sports science and nutrition courses, and for biomedical scientists and clinicians specializing in diabetes and inborn errors of metabolism.
Table of Contents
1. Introduction to the Metabolic Pathways.
2. Biosynthesis of ATP I: ATP, the Molecule that Powers Metabolism.
3. Biosynthesis of ATP II: Mitochondrial Respiratory Chain.
4. The Oxidation of Cytosolic NADH+H+: The Malate/Aspartate Shuttle and the Glycerol Phosphate Shuttle.
5. Metabolism of Glucose to Provide Energy.
6. Metabolism of One Molecule of Glucose Yields 31 (or should it be 38?) Molecules of ATP.
7. Metabolism of Glucose of Glycogen.
8. Anaerobic Metabolism of Glucose and Glycogen to Yield Energy as ATP.
9. 2,3-Bisphosphoglycerate (2,3-BPG) and the Red Blood Cell.
10. Metabolism of Glucose to Fat (triacylglycerol).
11. Metabolism of Glucose to Fatty Acids and Triacylglycerol.
12. The Pentose Phosphate Pathway and the Production of NADPH+H+.
13. The Pyruvate/Malate Cycle and the Production of NADPH+H+.
14. Mammals Cannot Synthesize Glucose from Fatty Acids.
15. Metabolism of Triacylglycerol to Provide Energy as ATP.
16. The Ornithine Cycle for t5he Production of Urea: ‘the Urea Cycle.’.
17. Biosynthesis of the Non-Essential Amino Acids.
18. Catabolism of Amino Acids.
19. Catabolism of Amino Acids.
20. Metabolism of Amino Acids to Glucose in Starvation and During the Period Immediately after Refeeding.
21. Metabolism of Protein to Fat.
22. Disorders of Amino Acid Metabolism.
23. Amino Acid Metabolism, Folate Metabolism and the ‘1-Carbon Pool’ I: Purine Biosynthesis.
24. Amino Acid Metabolism, Folate Metabolism and the ‘1-Carbon Pool’ II: Pyrimidine Biosynthesis.
25. Porphyrin Metabolism, Haem and the Bile Pigments.
26. Glycogen Metabolism I.
27. Glycogen Metabolism II.
28. Glycogen Metabolism III: Regulation of Glycogen Breakdown.
29. Glycogen Metabolism IV: Regulation of Glycogen Synthesis.
30. Regulation of Glycolysis.
31. Regulation of Krebs Cycle.
32. Regulation of Gluconeogenesis.
33. Regulation of Fatty Acid Oxidation I: Mobilization of Fatty Acids from Storage in Adipose Tissue.
34. Regulation of Fatty Oxidation II: The Carnitine Shuttle.
35. The Ketone Bodies.
36. Ketone Body Utilization.
37. B-Oxidation of Unsaturated Fatty Acids.
38. Peroxisomal B-Oxidation.
39. Elongation and Desaturation of Fatty Acids.
40. Cholesterol, Bile Acids and the Steroid Hormones.
41. Metabolism of Ethanol.
42. Sorbitol, Galactitol, Glucuronate and Xylitol.
43. Fructose Metabolism.
44. Biochemistry of Sport and Exercise.
45. Diabetes I: Insulin-Stimulated Glycogen Synthesis-Signal Transductionj.
46. Diabetes II: Metabolism Changes in Type 1 Diabetes.
47. Diabetes III: Type 1 Diabetes, Type 2 Diabetes, MODY and Pancreatic B-Cell Metabolism.
48. Diabetes IV: Type 2 Diabetes and Insulin Resistance in Muscle and Adipose Tissue.
49. Diabetes V: Type 2 Diabetes and Insulin Resistance in Liver.