Metagenomics for Microbiology

by Jacques Izard, Maria Rivera

Overview

Concisely discussing the application of high throughput analysis to move forward our understanding of microbial principles, Metagenomics for Microbiology provides a solid base for the design and analysis of omics studies for the characterization of microbial consortia. The intended audience includes clinical and environmental microbiologists, molecular biologists, infectious disease experts, statisticians, biostatisticians, and public health scientists. This book focuses on the technological underpinnings of metagenomic approaches and their conceptual and practical applications.

With the next-generation genomic sequencing revolution increasingly permitting researchers to decipher the coding information of the microbes living with us, we now have a unique capacity to compare multiple sites within individuals and at higher resolution and greater throughput than hitherto possible. The recent articulation of this paradigm points to unique possibilities for investigation of our dynamic relationship with these cellular communities, and excitingly the probing of their therapeutic potential in disease prevention or treatment of the future.

Product Details

ISBN-13:	9780124104723
Publisher:	Elsevier Science
Publication date:	11/13/2014
Pages:	188
Product dimensions:	5.90(w) x 8.90(h) x 0.50(d)

Table of Contents

Preface

1. Steps in Metagenomics: Let's Avoid Garbage In and Garbage Out
2. Long-Read, Single Molecule, Real-Time (SMRT) DNA Sequencing for Metagenomic Applications
3. Ribosomal RNA Removal methods for Microbial Transcriptomics
4. High Throughput Sequencing as a Tool for Exploring the Human Microbiome
5. Computational Tools for Taxonomic Microbiome Profiling of Shotgun Metagenomics
6. Hypothesis Testing of Metagenomic Data
7. Longitudinal Microbiome Data Analysis
8. Metagenomics for Bacteriology
9. Toward the Understanding of the Human Virome
10. Promises and Prospects of Microbiome Studies

Glossary

What People are Saying About This

From the Publisher

A practical and tailored review of design principles for interdisciplinary metagenomics studies

Editorial Reviews

"…an excellent book on the latest metagenomic methodologies and best practices in sample collection to data analysis for metagenomic and metatranscriptomic studies. Score: 80 - 3 Stars" —Doody's

From the Publisher

Reviewer: Omer Iqbal, MD, FACC, FESC (Loyola University Medical Center)
Description: This is a small, interesting book on the latest metagenomic methodologies and best practices, from sample collection to data analysis for taxonomic, whole shotgun metagenomic and metatranscriptomic studies.
Purpose: The purpose is to provide microbiologists generating metagenomic next generation sequencing data, an introduction to and support of the computational and statistical specifics of the data, and statisticians working in this area, some initial background.
Audience: The book is intended for researchers, teachers, and students and for scientists pursuing and interested in microbial metagenomic studies. In addition, it will be of interest to students and scientists and environmental molecular biologists, infectious disease experts, biostatisticians, and public health scientists interested in learning more about metagenomics.
Features: The 10 chapters cover interesting topics such as sample collection and preparation, data generation and quality control, third generation sequencing, advances in computational analysis of longitudinal data, and time series. The book ends with a very interesting chapter on promises and prospects of microbiome studies. The book has a good number of black-and-white figures to supplement the text.
Assessment: This is an excellent book on the latest metagenomic methodologies and best practices in sample collection to data analysis for metagenomic and metatranscriptomic studies.

Doody's Review Service