The current volume provides detailed experimental prools used to study plasma membrane ion channels as pharmacological targets. Coverage includes molecular and biochemical characterization of ion channels; fuctional analysis of ion channels after reconstitution, expression, or in cells; and specific methods and tools. This wealth of information will benefit academic and industrial researchers and graduate students in pharmacology, biochemistry, physiology, and biophysics.
|Edition description:||Softcover reprint of hardcover 1st ed. 1993|
|Product dimensions:||7.01(w) x 10.00(h) x 0.02(d)|
Table of ContentsMolecular and Biochemical Characterisation of Ion Channels: Purification and Pharmacologic Analysis of the OmegaConotoxin Receptor from Rat Brain (M. McEnery). Molecular Characterization of the CharybdotoxinSensitive, High Conductance, Calcium Activated Potassium Channel (M. GarciaCalco et al.). Functional Analysis of Ion Channels: Xenopus Oocytes as an Expression System for Ion Channels (A.L. Goldin). Reconstitution of Muscle Calcium Channel Function in Bilayer Membranes (D.J. Pelzer et al.). Specific Methods and Tools: Production of Monoclonal Antibodies Against Low Abundance, Ion Channel Associated Proteins in Neuronal Tissue (M. Takahashi). A Highly Porous Sodium DodecylsulfatePolyacrylamide System (J.P. Doucet et al.). Synthesis and Properties of Diazipine, a Novel Photoaffinity Probe for Calcium ChannelLinked DHP Receptors (H. Nakayama et al.). 4 additional articles. Index.