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Microbe: Are We Ready for the Next Plague?

Microbe: Are We Ready for the Next Plague?

by Alan Zelicoff, Michael Bellomo


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Product Details

ISBN-13: 9780814408650
Publisher: AMACOM
Publication date: 06/28/2005
Pages: 256
Product dimensions: 6.34(w) x 9.30(h) x 1.14(d)
Age Range: 17 Years

About the Author

"Alan P. Zelicoff, M.D. (Albuquerque, NM) is a physician, physicist, and senior scientist at Sandia National Laboratories, an engineering and science lab operated by Sandia Corporation for the US Department of Energy's National Nuclear Security Administration. The inventor of the Syndrome Reporting Information System for the rapid dissemination of disease information, he has written for The Washington Post and The Wall Street Journal.

Michael Bellomo (Burlingame, CA) holds a Six Sigma Black Belt certification and has worked for the Ares Corporation, a project and risk management firm that works with the Department of Defense, NASA, and the Department of Energy."

Table of Contents



Chapter 1: The Birds That Fell From the Sky — West Nile Virus

Chapter 2: A Corona of Death — SARS

Chapter 3: The Arroyo Muerte — Sin Nombre Hantavirus

Chapter 4: Outbreaks, Reservoirs and Dead End Hosts

Chapter 5: Shards of Glass in the Brain — Bovine Spongiform Encephalopathy (Mad Cow)

Chapter 6: Out of the Shadows — Legionella Pneumophila (Legionnaire’s Disease)

Chapter 7: An Ill Wind — Smallpox

Chapter 8: Natural Born Killers —Why Some Germs Stay Bad

Chapter 9: Something in the Water - Cholera, Cryptosporidiosis

Chapter 10: When Hours Count - but Days Don't Matter - Anthrax

Chapter 11 Pronouncing the Patient CURED

Chapter 12: Project BIOWATCH - Plague Vials Vanish in Texas

Chapter 13: A New Weapon in the Fight

Chapter 14: Gold Nuggets and Influenza Vaccines — DNA-based vaccines

Chapter 15: Three Ounces of Prevention — Scenarios involving Avian Bird Flu, Bioterrorism using Smallpox

Chapter 16: Into a Crystal Ball, Darkly...

Appendix A: Glossary

Appendix B: Letter to Lev Sandhakchiev"

What People are Saying About This

From the Publisher

"“This thought provoking book is a must read for anyone with concerns about or responsibility for early detection and containment of either emerging infectious diseases or the management of an epidemic caused by bioterrorism.

In this delightfully pithy volume, the authors manage to interweave the recounting of past public health system failures with some good introductory science and some important insights into the "clinical thought process". They conclude with straightforward recommendations for future actions.

The authors do a nice job explaining the nuances of prions and DNA vaccine and make a compelling case for strengthening the relationships between the public health, human and animal medical communities. The authors provide brief insights into several recent failures of the public health to detect and contain emerging infectious diseases before they became integrated into the nation's eco-systems. In recounting outbreaks of West Nile virus, cryptosporidium and bovine spongiform encephalopathy they raise a series of "what if" questions that should stimulate the reader to further readings.

The story of the Aralesk smallpox outbreak is in itself worth the price of the read. That relatively unknown smallpox outbreak caused by Soviet live agent testing, for once and for all, lays to rest some of the myths about the Soviets work to weaponize smallpox.

The book contains two illustrative bioterrorist scenarios, each of which is plausible and frighteningly realistic, and which by themselves make a compelling case for the nation's public health community to rapidly move to adopt a system of syndrome based disease surveillance.

It is those recurring discussions about the utility of syndrome-based surveillance that ultimately embody the book's central message. The clarity with which the authors discuss the strengths and weakness of the nation's current disease detection efforts and their shortfalls is refreshing and raises important policy issues. This book clearly illustrates the need for the nation to implement an emerging infectious diseases warning system that is syndrome-based rather than the one based on disease reporting. Hopefully, the public policy community as well as public health and clinical communities will read this book and act on its recommendations."x

— William D. Stanhope, Associate Director, Special Projects, Institute for Biosecurity, School of Public Health, Saint Louis University"

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