Mitochondrial Case Studies: Underlying Mechanisms and Diagnosis offers the science behind mitochondrial disease with a case studies approach. Since mitochondrial diseases are diverse and influenced by genetic, environmental, and social-economic factors, this publication will help students, physicians, scientists, health care students, and families recognize and accurately diagnose mitochondrial disease and learn about potential treatments.
- Reviews case studies as a helpful teaching tool to increase awareness and improve diagnosis
- Provides information on underlying mechanisms of mitochondrial disease
- Includes basic mitochondrial dysfunction research through patient case studies to best illustrate the entire disease process
|Sold by:||Barnes & Noble|
|File size:||9 MB|
About the Author
Sumit Parikh, MD is the Director of the Cleveland Clinic Neurogenetics, Metabolic&Mitochondrial disease program. Dr. Parikh completed his residency in pediatrics and fellowship in child neurology at the Children's Hospital of Pittsburgh. He received additional training in genetics and metabolism at Cleveland Clinic and Centers for Inherited Diseases of Metabolism. Dr. Parikh is part of the North American Mitochondrial Disease Research Consortium (NAMDC) and the Primary Investigator for the Pearson Syndrome Natural History study. He serves as the current chair of the United Mitochondrial Disease Foundation Scientific&Medical Advisor Board. He is the immediate Past-President of the Mitochondrial Medicine Society.
Table of Contents
1. Clinical Correlates of Mitochondrial Physiology and Disease 2. MELAS-encoded diseases 3. MELAS-(classic presentation) 4. MERRF 5. Pearson Syndrome 6. Kearn-Sayre Syndrome 7. Chronic Progressive External Ophthalmoplegia 8. Leber Hereditary Optic Neuropathy 9. Leigh Syndrome 10. NARP 11. Maternal Inherited Diabetes 12. Sporadic Myopathy 13. Pyruvate Dehydrogenase Complex Deficiencies 14. Friedreich Ataxia 15. Leigh Syndrome 16. Reversible Myopathy 17. Childhood Alpers-Huttenlocher Syndrome 18. Juvenile Alpers-Huttenlocher Syndrome 19. Autosomal dominant Progressive External Ophthalmoplegia 20. c10orf2 (Twinkle) 21. MPV17/Deoxyguanosine Kinase 22. RRM2B 23. Mitochondrial Nasogastric Intestinal Encephalopathy 24. Thymidine Kinase 25. OPA1 26. MFN2 27. Aminoacyl-tRNA synthetase (CNS) 28. Aminoacyl-tRNA synthetase (Non-CNS) 29. MTO1 30. Complex I 31. Complex II 32. Complex III (GRACILE) 33. Complex IV 34. Complex V 35. Coenzyme Q10 (Primary Brain) 36. Coenzyme Q10 (Primary Renal)