Modern Epidemiologic Principles and Concepts: Guidelines for Study Design, Conduct and Application

by Laurens Holmes

Overview

Modern Epidemiologic Principles & Concept: Guidelines for Study Design, Conduct & Application

This Modern Epidemiologic Principles and Concepts, as clinical medicine and public health text introduces the fundamental concepts in epidemiologic investigation and demonstrates how to integrate emerging research on epigenomics into practice, disease control and prevention.
Epidemiology has a vital strategic role in facilitating and leading evidence discovery in all aspects of human health, with the intent of improving patient and population health through disease risk determinants, disease control and prevention as well as health promotion practices. Emphasizing what we currently understand about the transformation the human body and the ecosystem undergo as a result of social structure, environment, daily challenges, and mutation, remain essential in disease improvement and population health optimization.

The first part of this text explores the origin of epidemiology, its relationship with medicine and public health, and its role in assessing disease distribution as occurrence or frequency, predisposing and risk factors, treatment and management. Further, it explains in detail, the specific epidemiologic design, conduct, analysis and interpretation. Furthermore , since epidemiology remains translational, this text explains several epidemiologic disciplines including although not limited to cancer epidemiology, nutrition epidemiology, environmental epidemiology, health disparities epidemiology, genetic epidemiology , an well as the elaboration of how the gene and environment interaction, termed epigenomic modulations as aberrant predispose to morbidity, prognosis, survival and mortality at individual as well as the specific population level. This 1st edition remains novel in the application of epigenomic modulations in epidemiologic investigation in disease incidence, morbidity and mortality at specific population level for graduate education in public health and clinical sciences as well as medical.

Product Details

BN ID:	2940184677163
Publisher:	Laurens Holmes, Jr
Publication date:	01/10/2025
Sold by:	Barnes & Noble
Format:	eBook
File size:	5 MB

About the Author

Laurens Holmes Jr specialized in Immunology & Infectious Disease as a component of Internal Medicine, as well as Neuro- Pharmacology. Currently he is an expert in Cancer Epidemiology and Biostatistical modeling, namely Signal Amplification and Risk Specific Stratification (SARSSm) with specific focus on epigenomic epidemiology. Dr. Holmes is a major proponent of aberrant epigenomic modulations in disease incidence, morbidity, prognosis, mortality and survival. This specialized discipline, epigenomic epidemiology was developed by Professor Holmes, in the application of aberrant epigenomic modulations in cancer risk determinants and induction therapy prior to the standard of care in malignant neoplasm. He is currently developing an epigenomic device in specific gene expression identification, and the application in genomic and epigenomic modulations in disease causation.

Dr. Holmes was a former Head of the Epidemiology Laboratory at the Nemours Center for Childhood Cancer Research, Wilmington, former Professor of Molecular Epidemiology and Clinical Trials at University of Delaware, USA. Professor Holmes, former director of Clinical & Translational Science Institute, Medical College of Wisconsin, Milwaukee has trained medical students, residents, fellows (doctorate/post-doctorate), and junior faculty on the application of epigenomic modulations in disease causation, therapeutics as induction therapy prior to the standard of care. He is currently the Editor-in-Chief, Pediatric Health, Medicine & Therapeutics, and Precision Medicine Research scientific journals. Dr. Holmes has published intensively in several scientific journals and several books in epidemiology, biostatistics, public health and, clinical medicine. Professor Holmes is currently the Director of the Graduate Public Health Program, Delaware State University, Dover, USA and Distinguished Professor, Public Health Institute, FAMU, Tallahassee, FL.