Molecular Basis of Neurological Disorders and Their Treatment

cyhemical techniques (ICC) which provide a useful adjunct to investigations by immunoblotting. A particular advantage of a cyhemical approach to the investigation of mihondrial disorders is that it allows the mosaic distribution of certain of these defects to be detected, whereas the tissue homogeniza­ tion involved in conventional enzyme assays or immunoblotting precludes this. A further advantage of MEA or ICC is that only small amounts of tissue are needed, which is important since many ...