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Multiple sclerosis (MS) is a devastating demyelinating disease with complex aetiology which defies simple molecular description. Molecular Biology of Multiple Sclerosis provides a compendium of information on the molecular aspects of the disease. It embraces contributions on the biology and pathology of the cells of the central nervous system as well as recent advances in our understanding of the relevant biochemistry, immunology, genetics and virology. With this enhanced knowledge the prospects for transplantation and repair of the damaged myelin as well as approaches to rational therapy are considered. Studies in MS embrace a wide spectrum of disciplines and this volume will be indispensible to neurologist, molecular biologists, biochemists, microbiologists, geneticists and immunologists with an interest in MS.
|Product dimensions:||6.14(w) x 9.29(h) x 0.79(d)|
Table of Contents
Partial table of contents:
Molecular Sclerosis—A Molecular Conundrum (W. Russell).
Molecular Cell Biology of Oligodendrocytes (K. Rogers, et al.).
Molecular Biology of the Glia: Components of Myelin—PLP and Minor Myelin Proteins (P. Montague & I. Griffiths).
Molecular Biology of the Glia: Astrocytes (S. Lee & C. Brosnan).
Molecular Biology of Microglia (M. Cuzner).
The Blood-Brain Barrier (B. Engelhardt).
B Cells and Autoimmunity (H. Link).
Genetic Aspects of MS (A. Spurkland & F. Vartdal).
Glycolipids of the CNS (M. Saito & R. Yu).
Viruses and MS (W. Russell).