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Molecular Hematology / Edition 2
     

Molecular Hematology / Edition 2

by Drew Provan, John Gribben
 

ISBN-10: 1405112557

ISBN-13: 9781405112550

Pub. Date: 02/28/2005

Publisher: Wiley

Now in its third edition, Molecular Hematology has been thoroughly updated to incorporate recent advances in molecular research. The aim of the book remains the same – to provide a core knowledge base for those with little exposure to molecular biological techniques.

Molecular biology has had a significant impact on the understanding of blood diseases

Overview

Now in its third edition, Molecular Hematology has been thoroughly updated to incorporate recent advances in molecular research. The aim of the book remains the same – to provide a core knowledge base for those with little exposure to molecular biological techniques.

Molecular biology has had a significant impact on the understanding of blood diseases and this book shows how molecular techniques can be used in diagnosis and treatment. In each chapter the authors summarize the impact made by molecular research on the understanding of the pathogenesis of the disorder featured, and highlight the molecular strategies that exist, or are being currently investigated, for therapeutic purposes. There are six brand new chapters in this edition:

  • History and development of molecular biology
  • Pharmacogenomics
  • Anemia of chronic disease
  • Molecular pathogenesis of malaria
  • Molecular basis of transplantation
  • Cancer stem cells

Presented in an extremely readable style with clear two-color line diagrams, this book is designed for the non-specialist and will be an invaluable resource for all trainee hematologists.

Product Details

ISBN-13:
9781405112550
Publisher:
Wiley
Publication date:
02/28/2005
Edition description:
REV
Pages:
344
Product dimensions:
8.40(w) x 10.90(h) x 1.00(d)

Table of Contents

List of contributorsvii
Forewordix
Prefacexi
Abbreviationsxiii
1Beginnings: the molecular pathology of haemoglobin1
2Molecular cytogenetics18
3Molecular basis of leukaemia and lymphoma25
4Detection of minimal residual disease in haematological malignancies42
5Chronic myeloid leukaemia61
6Myelodysplastic syndromes75
7Myeloproliferative disorders85
8Lymphoid neoplasms99
9The molecular biology of multiple myeloma110
10Haemoglobinopathies due to structural mutations121
11The molecular basis of anaemia134
12Molecular coagulation and thrombophilia158
13Molecular basis of haemophilia168
14The molecular basis of blood cell alloantigens182
15Haematopoietic growth factors198
16Molecular therapeutics in haematology209
Appendices225
Index231

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