Molecular Nuclear Medicine: The Challenge of Genomics and Proteomics to Clinical Practice

Molecular Nuclear Medicine: The Challenge of Genomics and Proteomics to Clinical Practice

Paperback(Softcover reprint of the original 1st ed. 2003)

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Product Details

ISBN-13: 9783642624278
Publisher: Springer Berlin Heidelberg
Publication date: 10/24/2012
Edition description: Softcover reprint of the original 1st ed. 2003
Pages: 795
Product dimensions: 7.60(w) x 10.63(h) x (d)

About the Author

Over six hundred fifty scientific publications, especially on cell biology, molecular nuclear medicine for in vivo analysis of biochemical reactions, cell responses to low doses of ionizing radiation and to strong static magnetic fields in single- and multi- cellular systems. - Member of numerous national and international advisory groups, committees, boards. Member, Northrhine-Westfalian Academy of Sciences, Germany. Vice-president, Committee for the Annual Meetings of Nobel Prize Winners in Lindau, Germany. Numerous scientific awards and prices.

Table of Contents

I Primary Topics.- 1 Measurements of Biochemical Reactions in Vivo.- 2 The Human Genome and Disease.- 3 Functional Genomics and Proteomics: Basics, Opportunities and Challenges.- 4 How Proteins Speak with One Another in Cell Signaling.- 5 Labeled Agents as Tracers and Carriers: Theory and Practice.- 6 Instrumentation for Measuring Metabolism.- 7 Modelling Metabolite and Tracer Kinetics.- 8 Compound Delivery and Local Blood Flows.- II Whole Body Processes.- 9 Endothelium and Compound Transfer.- 10 Coagulation and Peripheral Vascular Disease.- 11 Molecular Imaging of Infection and Inflammation.- 12 Element Metabolism and Body Composition.- 13 The Biology of Aging and Related Nuclear Medicine Studies.- 14 In Vitro Indicators of Metabolism of Natural Compounds.- III Organ Systems.- 15 Endocrinology.- 16 Noninvasive Assessment of Inherited Cardiac Disease Using Positron Emission Tomography.- 17 Molecular Background of 18F-2-deoxy-D- glucose (FDG) Uptake in the Ischemic Heart.- 18 Imaging Studies in Substance Abuse.- 19 Imaging of Cerebral Metabolism in Huntington’s Disease.- 20 Monoamine Oxidase: Radiotracer Development and Human Studies.- 21 Amino Acid Transport Studies in Brain Tumors.- 22 Lung.- 23 Functional Genomics and the Liver.- 24 Molecular Gastrointestinal Scintigraphy.- 25 The Kidney and Genital System.- 26 Biomolecular Magnification Imaging of Musculoskeletal Diseases.- IV Tumors.- 27 Molecular Imaging in Oncology.- 28 Nuclear (PET/SPECT) Imaging of Gene Expression: Methods and Applications.- 29 Development of DNA-based Radiopharma- ceuticals Carrying Auger-Electron Emitters for Anti-gene Radiotherapy.- V Special Topics.- 30 The Role of Nuclear Medicine in Relation to Alternative Modalities.- 31 MR Contrast Agents for Molecular and Cellular Imaging.- 32 Magnetic and Optical Molecular Imaging. Live Cell and Tissue Fluorescence: Imaging Techniques and Methods.- 33 Biological Effects of Low Doses of Ionizing Radiation: Damage versus Protection.

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