Pub. Date:
Springer-Verlag New York, LLC
Molecular Pathology of the Prions / Edition 1

Molecular Pathology of the Prions / Edition 1

by Harry F. Baker


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Product Details

ISBN-13: 9780896039247
Publisher: Springer-Verlag New York, LLC
Publication date: 07/13/2001
Series: Methods in Molecular Medicine , #59
Edition description: 2001
Pages: 279
Product dimensions: 6.10(w) x 9.25(h) x 0.03(d)

Table of Contents

What Would Thomas Henry Huxley Have Made of Prion Diseases?
Rosalind M. Ridley

Prion Protein as Copper-Binding Protein at the Synapse
Hans A. Kretzschmar, Tobias Tings, Axel Madlung, Armin Giese, and Jochen Herms

A Function for the Prion Protein?
David R. Brown and Ian M. Jones

Prion Protein Peptide: Agents of Death for Neurons
David R. Brown

Characterization of Bovine Spongiform Encephalopathy and Scrapie Strains/Isolates by Immunochemical Analysis of PrPSc
Martin H. Groschup, Frauke Junghans, Martin Eiden, and Thorsten Kuczius

Differential Targeting of Neurons by Prion Strains
Stephen J. DeArmond

Transgenic Studies of Prion Diseases
Glenn C. Telling

Prions: From Neurografts to Neuroinvasion
Markus Glatzel, Sebastian Brandner, Michael A. Klein, and Adriano Aguzzi

Cellular and Transgenic Models of Familial Prion Diseases
David A. Harris, Roberto Chiesa, Antonio Migheli, Pedro Piccardo, and Bernardino Ghetti

Central Nervous System Inflammation and Prion Disease Pathogenesis
Samar Betmouni and V. Hugh Perry

The Electroneuropathology of Prion Disease
J. Richard Greene

Transmissible Spongiform Encephalopathy Neurobiology and Ultrastructure Suggests Extracellular PrPSc Conversion Consistent with Classical Amyloidosis
Martin Jeffrey and Jan R. Fraser

Conformation as Therapeutic Target in the Prionoses and Other Neurodegenerative Conditions
Thomas Wisniewski, Einar M. Sigurdsson, Pierre Aucouturier, and Blas Frangione

Prions of Yeast: From Cytoplasmic Genes to Heritable Amyloidosis
Reed B. Wickner, Herman K. Edskes, Kimberly L. Taylor, Marie-Lise Maddelein, Hiromitsu Moriyama, and B. Tibor Roberts

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