The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease / Edition 1

The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease / Edition 1

Pub. Date:
Springer US


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The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease / Edition 1

Curcumin is derived from the root of the plant Curcuma longa (also called turmeric) and its medicinal uses have been described for over 5000 years. More than 1500 papers published within last half a century has revealed that curcumin has a potential in the treatment of wide variety of inflammatory diseases including cancer, diabetes, cardiovascular diseases, arthritis, Alzheimer, psoriasis etc, through modulation of numerous molecular targets. This is the first monograph to deal specifically with this subject.

Product Details

ISBN-13: 9780387464008
Publisher: Springer US
Publication date: 05/28/2007
Series: Advances in Experimental Medicine and Biology Series , #595
Edition description: 2007
Pages: 490
Product dimensions: 6.10(w) x 9.25(h) x 0.05(d)

Table of Contents

Curcumin: The Indian Solid Gold   Bharat B. Aggarwal   Chitra Sundaram   Nikita Malani   Haruyo Ichikawa     1
Highly Active Anticancer Curcumin Analogues   Cara A. Mosley   Dennis C. Liotta   James P. Snyder     77
Antioxidant and Anti-Inflammatory Properties of Curcumin   Venugopal P. Menon   Adluri Ram Sudheer     105
Modulation of Transcription Factors by Curcumin   Shishir Shishodia   Tulika Singh   Madan M. Chaturvedi     127
Cancer Chemopreventive Effects of Curcumin   Young-Joon Surh   Kyung-Soo Chun     149
Antitumor, Anti-Invasion, and Antimetastatic Effects of Curcumin   Girija Kuttan   Kuzhuvelil B. Hari Kumar   Chandrasekharan Guruvayoorappan   Ramadasan Kuttan     173
Curcumin as an Inhibitor of Angiogenesis   Sulochana S. Bhandarkar   Jack L. Arbiser     185
Neuroprotective Effects of Curcumin   Greg M. Cole   Bruce Teter   Sally A. Frautschy     197
Regulation of Cox and Lox by Curcumin   Chinthalapally V. Rao     213
Molecular Targets of Curcumin   Jen-Kun Lin     227
Cell Growth Regulation   DevarajanKarunagaran   Jeena Joseph   Thankayyan R. Santhosh Kumar     245
Curcumin as Chemosensitizer   Pornngarm Limtrakul     269
Radioprotection and Radiosensitization by Curcumin   Ganesh C. Jagetia     301
Immunomodulation by Curcumin   Subhash C. Gautam   Xiaohua Gao   Scott Dulchavsky     321
Beneficial Role of Curcumin in Skin Diseases   Rajesh L. Thangapazham   Anuj Sharma   Radha K. Maheshwari     343
Cardioprotective Effects of Curcumin   Sumitra Miriyala   Manikandan Panchatcharam   Puvanakrishnan Rengarajulu     359
Protection from Acute and Chronic Lung Diseases by Curcumin   Narayanan Venkatesan   Durairaj Punithavathi   Mary Babu     379
Nephroprotective and Hepatoprotective Effects of Curcuminoids   Toshihiko Osawa     407
Curcumin and Autoimmune Disease   John J. Bright     425
Pharmacokinetics and Pharmacodynamics of Curcumin   Ricky A. Sharma   William P. Steward   Andreas J. Gescher     453
Clinical Studies with Curcumin   Chih-Hung Hsu   Ann-Lii Cheng     471
Index     481

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