Molecules in Physics, Chemistry, and Biology: Molecular Phenomena in Biological Sciences

Molecules in Physics, Chemistry, and Biology: Molecular Phenomena in Biological Sciences

by J. Maruani (Editor)

Paperback(Softcover reprint of the original 1st ed. 1989)

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Volume 1: General Introduction to Molecular Sciences
Volume 2: Physical Aspects of Molecular Systems
Volume 3: Electronic Structure and Chemical Reactivity
Volume 4: Molecular Phenomena in Biological Sciences

Product Details

ISBN-13: 9789401070225
Publisher: Springer Netherlands
Publication date: 05/14/2013
Series: Topics in Molecular Organization and Engineering , #4
Edition description: Softcover reprint of the original 1st ed. 1989
Pages: 353
Product dimensions: 6.10(w) x 9.25(h) x 0.03(d)

Table of Contents

Biomolecular Evolution.- Randomness and Natural Selection in Genome Evolution.- 1. Introduction.- 2. The Compositional Compartmentalization of Genomes.- 3. Compositional Constraints Affect both Coding and Non-Coding Sequences.- 4. GC Increases in Coding Sequences Affect mRNA and Protein Stability.- 5. Compositional Constraints are Due to Environmental Pressures.- 6. Codon Usage is Largely Determined by Compositional Constraints.- 7. Mutations are Mainly Fixed through Natural Selection.- 8. Conclusions.- Acknowledgements.- References.- New Insights into the Evolution of Proteins.- 1. The Gene Determinism of the Protein Morphology.- 2. The Composite Organization of Proteins.- 3. The Repetitive Propensity within Proteins.- 4. Protein Polymorphism and the Multigene Family.- 5. Conclusion.- References.- Biomolecular Chirality.- Origin of the L-Homochirality of Amino-Acids in the Proteins of Living Organisms.- 1. Introduction.- 2. Stability of L-Forms.- 3. In Quest of Factors Able to Explain the L/D Discrimination.- 4. The Amplification Mechanism.- 5. A Possible Schema for the Appearance of Life.- 6. The Asymmetric Adsorption on Kaolinite.- 7. Weak Interactions or Asymmetric Adsorption?.- 8. Is the Universe Chiral?.- References.- Right-Handed and Left-Handed Molecular Structures.- 1. Introduction.- 2. The Chiral Molecule.- 3. The Origin of Chirality.- 4. Life and Chirality.- 5. Conclusion.- Acknowledgements.- References.- Molecular Pathology.- The Adventure of Molecules in Pathology.- 1. Introduction.- 2. Mendelian Hereditary Diseases.- 3. Polygenic Diseases.- 4. Acquired Molecular Diseases.- References.- Metallo-Organic Complexes and Carcinogenesis.- 1. Introduction.- 2. Possibilities of Raman Spectroscopy.- 3. Blue Particles in Cancer Bloods and Tumours.- 4. Micro-Raman Spectra of Cancer Blue Particles.- 5. Model Organo-Metallic Complexes.- 6. Comparative Analysis of the Raman Spectra.- 7. A Mechanism of Carcinogenesis.- 8. Selective Reactivity of Cancer Drugs.- 9. A Way Toward Therapeutic Research.- 10. A Way Toward Pharmaceutical Research.- 11. Conclusion.- Acknowledgements.- References.- Topics in Biomolecular Physics.- Vibrational Spectroscopy, Molecular Flexibility and Molecular Graphics.- 1. Vibrational Spectroscopy and the Theoretical Determination of Molecular Vibrations.- 2. The Biological Significance of Low-Frequency Molecular Vibrations.- 3. The Local Symmetry Force Field.- 4. Molecular Graphics and a Direct Visualization of Molecular Vibrations.- 5. Low Frequency Molecular Vibrations of the Z-Form of DNA.- 6. Conclusions and Perspectives.- References.- Collective Excitations in Biological Macromolecules: Photoelectron and Exciton Spectra of Polyene, Polypeptides and Polynucleotides.- 1. Introduction.- 2. Hartree—Fock Calculations on Biological Macromolecules.- 3. Beyond Hartree—Fock: Perturbation Theory of Electron Correlation in Biopolymers.- 4. Calculation of Ground State Energy Levels in Polyene, Polypeptides and Polynucleotides.- 5. Electronically Excited States of Biological Macromolecules.- 6. Interaction of Polymers with an External Electromagnetic Field.- References.- The Problem of Protonation in Rhodopsin and Model Schiff Bases.- 1. Introduction.- 2. Why Invoke Protonation?.- 3. What Evidence Do We Have that the Chromophore Is Protonated?.- 4. How Can the Schiff Base Be Protonated in Rh?.- 5. What Difference Would It Make if the Schiff Base Was Not Protonated?.- References.- Molecular Neurobiology and Sociobiology.- Modeling the Drug-Receptor Interaction in Quantum Pharmacology.- 1. Introduction.- 2. The Drug-Receptor Interaction.- 3. A Practical Example: The Serotonin Receptor Binding Affinity.- Acknowledgements.- References.- Raman and Infrared Study of Acetylcholine and Postsynaptic Membranes.- 1. Introduction.- 2. Principles of the Methods.- 3. Biological Characteristics of the Samples.- 4. Sample Preparation.- 5. Technical Procedures.- 6. Vibrational Frequency Assignment.- 7. Experimental Results.- 8. Conclusion.- Acknowledgements.- References.- Molecules as Signal Transmitters in Biological Systems.- 1. Introduction.- 2. Transport.- 3. Reception.- 4. Transduction.- 5. Coding.- 6. Integration.- 7. Conclusion.- References.- Molecular Cues in Salmonid Migration.- 1. Introduction.- 2. The Biologist’ Confirmation.- 3. The Olfactory Sense and Selection of Tributaries.- 4. The Olfactory Sense and Navigation at Sea.- 5. The Pheromone Hypothesis.- 6. The Olfactory Epithelium.- 7. The Olfactory Bulb.- 8. Odorants from the Fish.- 9. Conclusion.- Acknowledgements.- References.- Molecules in Mammalian Communication.- 1. Introduction.- 2. Molecules Used by Mammals for Communication.- 3. Sources of Mammalian Chemosignals.- 4. Functions of Mammalian Pheromones.- 5. Can the Choice of a Molecule Be Predicted from the Function of a Pheromone?.- 6. Chemoreception and Stimulus-Response Relationships.- 7. The Mammalian Type of Pheromone Action.- Acknowledgements.- References.

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