ISBN-10:
047005820X
ISBN-13:
9780470058206
Pub. Date:
09/16/2008
Publisher:
Wiley
Multivariate Methods in Chromatography: A Practical Guide / Edition 1

Multivariate Methods in Chromatography: A Practical Guide / Edition 1

by Tibor Cserhati

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Product Details

ISBN-13: 9780470058206
Publisher: Wiley
Publication date: 09/16/2008
Pages: 352
Product dimensions: 6.80(w) x 9.80(h) x 1.00(d)

About the Author

Professor Tibor Cserhati, Chemical Research Centre, Research Institute of Materials and Environmental Chemistry, Hungarian Academy of Sciences, Budapest, HungaryGraduated in Chemical Engineering in 1962 and received his PhD in 1973 from the Technical University of Budapest. From 1975 - 1988 he was a senior research scientists at the Plant Protection Institute of the Hungarian Academy of Sciences and from 1989 scientific counsellor at the Central Research Institute for Chemistry. He is the author/coauthor of more than 500 papers and 5 books. His main fields of interest are various chromatographic methods including TLC, GC and HPLC and the application of multivariate methods for the evaluation of chromatographic data.

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Table of Contents

Preface.

Introduction.

List of Abbreviations, Acronyms and Symbols.

Chapter 1. Fundamentals.

1.1. Multilinear and nonlinear regression analyses.

1.2. Stepwise regression analysis and partial least squaresmethod.

1.3. Two and three-dimensional principal component analysis,various factor analytical techniques.

1.4. Canonical correlation analysis.

1.5. Discriminance analysis.

1.6. Spectral mapping.

1.7 Nonlinear mapping.

1.8. Cluster analysis.

1.9. Other multivariate techniques (fixed-size window movement,rank annihilation, etc).

1.10. Measured and calculated physicochemical parameters ofchromatographis systems and analytes.

Chapter 2. Gas Chromatography (GC).

2.1. Theory and practice of gas chromatography.

2.2. Comparison of GC stationary phases using homogenous andnon-homogenous set of analytes.

2.3. Elucidation of similarities and dissimilarities amongsamples.

2.3.1. Human health and pharmaceuticals.

2.3.2. Forensic analyses.

2.3.3. Biology and agrobiology.

2.3.4. Food and food products.

2.3.4.1. Wines.

2.3.4.2. Oils.

2.3.4.3. Foods of plant origin.

2.3.4.4. Miscellaneous food products.

2.3.5. Environmental analyses.

2.3.5.1. Volatile organic compounds (VOC), polycyclic aromatichydrocarbons (PAH), and polychlorinated biphenyls (PCB).

2.3.5.2. Miscellaneous environmental pollutants.

2.3.5.3. Gasoline.

2.3.6. Other synthetic compounds.

2.3.7. Miscellaneous applications.

Chapter 3. Liquid Chromatography (LC).

3.1. Thin-layer chromatography (TLC).

3.1.1. Theory and practice of thin-layer chromatography.

3.1.2. Multidimensional classification of TLC stationary and/ormobile phases.

3.1.3. Relationships between molecular parameters and TLCretention of analytes.

3.1.3.1. Pharmaceuticals and natural organic compounds.

3.1.3.2. Fatty acids and bile acids.

3.1.3.3. Pesticides and pesticide adjuvants.

3.1.4. Relationship between TLC retention parameters andbiological activity of analytes..

3.1.5. Miscellaneous applications.

3.2. High performance liquid chromatography (HPLC).

3.2.1. Theory and practice of HPLC.

3.2.2. Multidivariate classification of HPLC stationary and/ormobile phases.

3.2.2.1. Classification of stationary or mobile phases.

3.2.2.1.1. Principal component analysis (PCA).

3.2.2.1.2. Other multivariate techniques.

3.2.2.4. Classification of chromatographic systems.

3.2.2.4.1. Multilinear and multi nonlinear regression analyses(MLR and MNLR).

3.2.2.4.2. Principal component analysis (PCA), cluster analysis(CA) and other multivariate techniques.

3.2.3. Differentiation between homologous and non-homologouessets of analytes.

3.2.3.1. Human health.

3.2.3.2. Biological applications.

3.2.3.3. Agrobiochemistry.

3.2.3.4. Microbiology.

3.2.3.5. Natural (herbal) medicines.

3.2.3.6. Synthetic pharmaceuticals.

3.2.3.7. Wines.

3.2.3.8. Cheeses.

3.2.3.9. Miscellaneous foods and food products.

3.2.3.10. Polycyclic aromatic hydrocarbons.

3.2.3.11. Pesticides and homologous series of pollutants.

3.2.3.12. Non homologous series of pollutants.

3.2.3.13. Other environmental pollutants.

3.2.3.14. Miscellaneous HPLC applications.

Chapter 4. Electrically Driven Systems.

4.1. Theory and practice of electrically driven systems.

4.2. Gel electrophoretic techniques.

4.2.1. Theory and human health aspects.

4.2.2. Microorganisms.

4.2.3. Microbial communities.

4.2.4. Plant tissues.

4.3. Capillary zone electrophoresis (CZE).

4.3.1. New advances in CZE theory.

4.3.2. Human health and pharmacology.

4.3.3. Other applications.

4.4. Micellar electrokinetic chromatography (MEKC) and relatedtechnologies.

Index.

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