Myocardial Ischemia and Lipid Metabolism

Myocardial Ischemia and Lipid Metabolism

by R. Ferrari (Editor)


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Product Details

ISBN-13: 9781468448672
Publisher: Springer US
Publication date: 03/13/2012
Edition description: 1984
Pages: 342
Product dimensions: 6.69(w) x 9.61(h) x 0.03(d)

Table of Contents

Lipid Metabolism in the Myocardium.- Overview of Lipid Metabolism.- Factors Influencing the Carnitine-Dependent Oxidation of Fatty Acids in the Heart.- Localization and Function of Lipases and Their Reaction Products in Rat Heart.- Ultrastructural Localization of Lipids in Myocardial Membranes.- Lipid Induced Membrane Abnormalities.- Phospholipase-Induced Abnormalities in the Sarcolemma.- A Surface Charge Hypothesis for the Actions of Palmitylcarnitine on the Kinetics of Excitatory Ionic Currents in Heart.- Modulation of Membrane Function by Lipid Intermediates: A Possible Role in Myocardial Ischemia.- Fatty Acid Effects on Sarcoplasmic Reticulum Function In Vitro.- Ischemia and Lipid-Induced Changes in Myocardial Function.- Factors Influencing the Metabolic and Functional Alterations Induced by Ischemia and Reperfusion.- Factors that Influence Myocardial Levels of Long-Chain Acyl CoA and Acyl Carnitine.- Are Tissue Non-Esterified Fatty Acids (NEFA) Involved in the Impairment of Biochemical and Mechanical Processes during Acute Regional Ischemia in the Heart.- Effects of Myocardial Ischemia and Long Chain Acyl CoA on Mitochondrial Adenine Nucleotide Translocator.- Interventions Used to Modify Lipid-Induced Abnormalities in the Heart.- Fatty Acid and Carnitine-Linked Abnormalities during Ischemia and Cardiomyopathy.- Consequences of Fatty Acid Excess in Ischemic Myocardium and Effects of Therapeutic Interventions.- Membrane Phospholipid Metabolism during Myocardial Ischemia: Mechanisms of Accumulation of Unesterified Arachidonate.- Phospholipase and Ischemic Damage: Possibilities of Interventions.- Importance of Lipid Metabolism in Man.- Cardiac Perfusion, Past and Present.- Clinical Relevance of Free Fatty Acid Excess.- Iodine-123 Phenylpentadecanoic Acid: Detection of Acute Myocardial Infarction in Anesthetized Dogs.- Free Fatty Acid, Catecholamines and Arrhythmias in Man.- Conclusions.- Contributors.

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