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Name Reactions in Heterocyclic Chemistry II / Edition 1

Name Reactions in Heterocyclic Chemistry II / Edition 1

by Jie Jack Li, E. J. Corey


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Name Reactions in Heterocyclic Chemistry II / Edition 1

The up-to-DATE guide to name reactions in heterocyclicchemistry

Name Reactions in Heterocyclic Chemistry II presents acomprehensive treatise on name reactions in heterocyclic chemistry,one of the most exciting—and important—fields withinorganic chemistry today.

The book not only covers fresh ground, but also providesextensive information on new and/or expanded reactions in:

  • Three- and four-membered heterocycles

  • Five-membered heterocycles (pyrroles and pyrrolidines, indoles,furans, thiophenes, and oxazoles)

  • Six-membered heterocycles, including pyridines, quinolines, andisoquinolines

Featuring contributions from the leading authorities inheterocyclic chemistry. Each section includes a description of thegiven reaction, as well as the relevant historical perspective,mechanism, variations and improvements, synthetic utilities,experimental details, and references to the current primaryliterature.

The reactions covered in Name Reactions in HeterocyclicChemistry have been widely adopted in all areas of organicsynthesis, from the medicinal/pharmaceutical field, to agriculture,to fine chemicals, and the book brings the most cutting-edgeknowledge to practicing synthetic chemists and students, along withthe tools needed to synthesize new and useful molecules.

Product Details

ISBN-13: 9780470085080
Publisher: Wiley
Publication date: 09/13/2011
Series: Comprehensive Name Reactions Series , #6
Pages: 704
Product dimensions: 7.60(w) x 9.30(h) x 1.60(d)

About the Author

Jie Jack Li is a Chemist at Bristol-Myers Squibb Company. He has authored or edited various books, including the first volume of Name Reactions in Heterocyclic Chemistry, Name Reactions for Functional Group Transformations, Name Reactions for Carbocyclic Ring Formations, and several others, all published by Wiley.

Table of Contents



Contributing Authors.


Chapter 1 Aziridines and Epoxides.

1.1 Blum Aziridine Synthesis.

1.2 Gabriel–Heine Aziridine Isomerization.

1.3 Shi Epoxidation.


Chapter 2 Pyrroles and Pyrrolidines.

2.1 Clauson–Kass Pyrrole Synthesis.

2.2 Houben–Hoech Acylation of Pyrroles.

2.3 Overman Pyrrolidine Synthesis.

2.4 Trofimov Synthesis of Pyrroles.

Chapter 3 Indoles.

3.1 Bischler–Möhlau Indole Synthesis.

3.2 Borsche–Drechsel Cyclization.

3.3 Buchwald–Hartwig Indole Synthesis.

3.4 Cadogan–Sundberg Indole Synthesis.

3.5 Fukuyama Indole Synthesis.

3.6 Gassman Oxindole Synthesis.

3.7 Larock Indole Synthesis.

3.8 Matinet Dioxindole Synthesis.

3.9 Mori–Ban Indole Synthesis.

3.10 Sandmeyer Isatin Synthesis.

3.11 Sommelet–Hauser Rearrangement.

3.12 Stollé Oxindole Synthesis.

Chapter 4 Furans and Oxazoles.

4.1 Nierenstein Reaction.

4.2 Davidson Oxazole Synthesis.

4.3 Fischer Oxazole Synthesis.

4.4 Japp Oxazole Synthesis.

4.5 Schöllkopf Oxazole Synthesis.

Chapter 5 Other Five-Membered Heterocycles.

5.1 Bamberger Imidazole Cleavage.

5.2 Dimroth Triazole Synthesis.

5.3 Finnegan Tetrazole Synthesis.

5.4 Hantsch Thiazole Synthesis.

5.5 Huisgen Tetrazole Rearrangement.

5.6 Knorr Pyrazole Synthesis.

5.7 Pechmann Pyrazole Synthesis.


Chapter 6 Pyridines.

6.1 Baeyer Pyridine Synthesis.

6.2 Katrizky Reaction.

Chapter 7 Quinolines and Isoquinolines.

7.1 Betti reaction.

7.2 Bernthsen Acridine Synthesis.

7.3 Lehmstedt–Tanasescu Reaction.

7.4 Niementowski Quinoline Synthesis.

7.5 Povarov Reaction.

Chapter 8 Six-Membered Heterocycles.

8.1 Balaban–Nenitzescu–Praill Reaction.

8.2 Borsche Cinnoline Synthesis.

8.3 Gutknecht Pyrazine Synthesis.

8.4 Niementowski Quinazoline Synthesis.

8.5 Pechmann Coumarin Synthesis.

8.6 Robinson–Schöpf Condensation.

8.7 Simonis Chromone Cyclization.

8.8 Wesseley–Moser Rearrangement.

8.9 Widman–Stoermer Cinnoline Synthesis.

8.10 Wichterle Reaction.

Chapter 9 Miscellaneous Name Reactions.

9.1 ANRORC Mechanism.

9.2 Boulton–Katritzky Rearrangement.

9.3 Chichibabin Amination Reaction.

9.4 Dimroth Rearrangement.

9.5 Hantzsch Synthesis.

9.6 Ortoleva–King Reaction.


Appendix 1, Table of Contents for Volume 1: Name Reactions inHeterocyclic Chemistry.

Appendix 2, Table of Contents for Volume 2: Name Reactionsfor Functional Group Transformations.

Appendix 3, Table of Contents for Volume 3: Name Reactionsfor Homologations-I.

Appendix 4, Table of Contents for Volume 4: Name Reactionsfor Homologations-II.

Appendix 5, Table of Contents for Volume 5: Name Reactionsfor Ring Formations.

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