The cutting-edge guide on advancing the science ofmolecular imaging using nanoparticles
Nanoplathform-Based Molecular Imaging provides rationale forusing nanoparticle-based probes for molecular imaging, thendiscusses general strategies for this underutilized, yet promising,technology. It addresses general strategies of particle synthesisand surface chemistry, applications in computed tomography opticalimaging, magnetic resonance imaging, ultrasound, multimodalityimaging, theranostics, and finally, the clinical perspectives ofnanoimaging. This comprehensive volume summarizes the opinions ofthose in the forefront of research and describes the latestdevelopments by emphasizing fundamentals and initiating hands-onapplication.
|Product dimensions:||7.90(w) x 10.20(h) x 1.90(d)|
About the Author
Xiaoyuan Chen received his PhD in chemistry from the University of Idaho and was an Associate Professor of Radiology in the School of Medicine at Stanford University before joining the National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH) as a senior investigator and the Laboratory of Molecular Imaging and Nanomedicine (LOMIN) as chief. He is the author of more than 200 scholarly articles and has edited one book to date. Dr. Chen's research interests include developing and validating novel molecular imaging probes (nanoparticles, antibodies, proteins, peptides, and small organic molecules) for better understanding of the biology, early diagnosis of disease, monitoring therapy response, and guiding drug discovery and development.
Table of Contents
Part I Basics of Molecular Imaging andNanobiotechnology.
1. Basic Principles of Molecular Imaging (Sven H.Hausner).
2. Synthesis of Nanomaterials as a Platform for MolecularImaging (Jinhao Gao, Jin Xie, Bing Xu, and XiaoyuanChen).
3. Nanoparticle Surface Modification and Bioocnjugation (JinXie, Jinhao Gao, Mark Michalski, and Xiaoyuan Chen).
4. Biodistribution and Pharmacokinetics of Nanoprobes (NageshKolishetti, Frank Alexis, Eric M. Pridgen, and Omid C.Farokhzad).
Part II Nanoparticles for Single Modality MolecularImaging.
5. Computed Tomography as a Tool for Anatomical andMolecular Imaging (Pingyu Liu, Hu Zhou, and Lei Xing).
6. Carbon Nanotube X-Ray for Dynamic Micro-CT Imaging of SmallAnimal Models (Otto Zhou, Guohua Cao, Yueh Z. Lee, and JianpingLu).
7. Quantum Dots for In Vivo Molecular Imaging (YunXing).
8. Biopolymer, Dendrimer and Liposome Nanoplatforms for OpticalMolecular Imaging (David Pham, Ling Zhang, Bo Chen, and Ella F.Jones).
9. Nanoplatforms for Raman Molecular Imaging in BiologicalSystems (Zhuang Liu).
10. Single-Walled Carbon Nanotube Near-Infrared FluorescentSensors for Biological Systems (Jingqing Zhang, and Michael S.Strano).
11. Microparticle- and Nanoparticle-Based Contrast-EnhancedUltrasound Imaging (Nirupama Deshpande, and Jurgen K.Willmann).
12. Ultrasound-Based Molecular Imaging Using Nanoagents(Srivalleesha Mallidi, Mohammad Mehrmohammadi, Kimberly Homan,Bo Wang, Min Qu, Timothy Larson, Konstantin Sokolov, and StanislavEmelianov).
13. MRI Contrast Agents Based on Inorganic Nanoparticles(Hyon B. Na, and Taghwan Hyeon).
14. Cellular Magnetic Labeling with Iron Oxide Nanoparticles(Sebastien Boutry, Sophie Laurent, Luce V. Elst, and Robert N.Muller).
15. Nanoparticles Containing Rare Earth Ions: A TunableTool for MRI (C. Riviére, S. Roux, R. Bazzi, J.-L. Bridot,C. Billotey, P. Perriat, and O. Tillement).
16. Microfabricated Multispectral MRI Contrast Agents (GaryZabow, and Alan Koretsky).
17. Radiolabeled Nanoplatforms: Imaging Hot Bullets HittingTheir Targets (Raffaella Rossin).
Part III: Nanoparticle Platforms as Multimodality Imaging andTherapy Agents.
18. Lipoprotein-Based Nanoplatforms for Cancer Molecular Imaging(Ian R. Corbin, Kenneth Ng, and Gang Zheng).
19. Protein Cages as Multimode Imaging Agents (Masaki Uchida,Lars Liepold, Peter Suci, Mark Young, and Trevor Douglas).
20. Biomedical Applications of Single-Walled Carbon Nanotubes(Weibo Cai, Ting Gao, and Hao Hong).
21. Multifunctional Nanoparticles for Multimodal MolecularImaging (Yonglong Hou, and Rui Hao).
22. Multifunctional Nanoparticles for Cancer Theragnostics(Seulki Lee, Ick Chan Kwon, and Kwangmeyung Kim).
23. Nanoparticles for Combined Cancer Imaging and Therapy(Vaishali Bagolkot, Mikyung Yu, and Sangyong Jon).
24. Multimodal Imaging and Therapy with MagnetofluorescentNanoparticles (Jason McCarthy, and Ralph Weissleder).
25. Gold Nanocages: A Multifunctional Platform for MolecularOptical Imaging and Photothermal Treatment (Leslie Au, Claire M.Cobley, Jingyi Chen, and Younan Xia).
26. Theranostic Applications of Gold Nanoparticles in Cancer(Parmeswaran Diagaradjane, Pranshu Mohindra, and SunilKrishnan).
27. Gold Nanorods as Theranostic Agents (Alexander Wei,Qingshan Wei, and Alexei P. Lenov).
28. Theranostic Applications of Gold Core-Shell StructuredNanoparticles (Wei Lu, Marites Melancon, and Chun Li).
29. Magnetic Nanoparticle Carrier for Targeted Drug Delivery:Perspective, Outlook and Design (R.D.K. Misra).
30. Perfluorocarbon Nanoparticles: A Multidimensional Platformfor Targeted Image-Guided Drug Delivery (Gregory M. Lanza,Shelton D. Caruthers, Anne H. Schmieder, Patrick M. Winter,Tillmann Cyrue, Samuel and A. Wickline).
31. Radioimmunonanoparticles for Cancer Imaging and Therapy(Arutselvan Natarajan).
Part IV: Translational Nanomedicine.
32. Current Status and Future Prospects for Nanoparticle-BasedTechnology in Human Medicine (Nuria Sanvicens, Fatima Fernandez,J.-Pablo Salvador, and M.-Pilar Marco).
What People are Saying About This
“This comprehensive volume summarizes the opinions of those in the forefront of research and describes the latest developments by emphasizing fundamentals and initiating hands-on application.” (Imaging & Microscopy, 1 March 2012)
"This monumental work of more than 800 pages is dedicated to the visualization of cellular behavior and molecular processes in living organisms using nanotechnologies. The book is written in a clear manner by tens of experts in the field." (Optics & Photonics News, 2011)
"This comprehensive volume summarizes the opinions of those in the forefront of research and describes the latest developments by emphasizing fundamentals and initiating hands-on application." (Global Print Monitor, 8 March 2011)