ISBN-10:
0262513870
ISBN-13:
9780262513876
Pub. Date:
01/01/2003
Publisher:
MIT Press
Neural Transplantation: An Introduction

Neural Transplantation: An Introduction

by William J. Freed

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Product Details

ISBN-13: 9780262513876
Publisher: MIT Press
Publication date: 01/01/2003
Series: Cellular and Molecular Neuroscience Series
Pages: 573
Product dimensions: 6.20(w) x 9.10(h) x 1.60(d)
Age Range: 18 Years

About the Author


William Freed is Principal Investigator at the National Institutes of Health at the National Institute on Drug Abuse Intramural Research Program in the Cellular Neurobiology Research Branch.

Table of Contents

Preface vii
Acknowledgments xi
I Introduction 1(30)
Introduction to Transplantation in the Nervous System
3(8)
Brain Structure and Development
11(20)
II General and Background Information 31(76)
History of Neural Transplantation
33(12)
Transplants and How They Are Used
45(26)
Control Groups and Experiments
71(10)
Regulations and Guidelines for Fetal Tissue Transplantation
81(10)
Mind Control and Other Things to Worry About
91(16)
III Parkinson's Disease 107(134)
Neural Systems and Parkinson's Disease
109(16)
Neural Transplantation in Parkinson's Disease: A Brief Synopsis
125(16)
Fetal Brain Tissue Transplantation in Parkinson's Disease: Experiments in Animals
141(28)
Adrenal Medulla Transplantation
169(22)
Studies in Subhuman Primates
191(10)
Fetal Brain Tissue Transplantation in Parkinson's Disease: Clinical Studies
201(40)
IV Using Transplants to Influence Localized Brain Functions 241(46)
Pain
243(16)
Hypothalamus and Pituitary
259(14)
The Cerebral Cortex and Stroke
273(14)
V Circuit Reconstruction 287(86)
Huntington's Disease
289(24)
Spinal Cord
313(48)
Visual System
361(12)
VI Genetic Engineering and Technology of the Future 373(76)
Introduction to Genetic Engineering and Neural Transplantation
375(12)
Growing Cells in Culture: Stem and Progenitor Cells
387(12)
Growing Cells in Culture: Immortal Cell Lines
399(26)
Genetically Modified Cells for Producing Neurotrophic Factors and Neurotransmitters
425(14)
Direct Gene Transfer
439(10)
VII Conclusions 449(28)
Conclusions
451(26)
Glossary 477(22)
References 499(44)
Index 543

What People are Saying About This

Jill B. Becker

This book is engaging and insightful, and has little gems of information throughout.
It will prove accessible for a large educated audience, yet will also hold the interest of experts in the field. I highly recommend it.

Ian Q. Whishaw

Students who want a readable and comprehensive summary of one of the great detective stories of the twentieth century should read Neural Transplantation. William J. Freed, one of the major participants in this story, describes research in which memories are transferred, the symptoms of brain diseases are ameliorated, and damaged brain tissue is replaced. Finally, he describes the directions which research that resembles science fiction is going.

From the Publisher

"This book is engaging and insightful, and has little gems of informationthroughout.

It will prove accessible for a large educated audience, yetwill also hold the interest of experts in the field. I highly recommendit." Jill B. Becker , Professor of Psychology, TheUniversity of Michigan, Ann Arbor

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