This book was developed from a course of lectures and practicals given to first-and second-year medical students at the University of Leeds. My aim has been to provide a comprehensive account of the nervous system and its functions, which I hope will help the student to attain a better understand ing of clinical neurology. For this reason a good deal of attention has been paid to the study of control systems, and emphasis laid on those mechanisms that are frequently deranged by injury or disease. In particu lar, a useful coverage has been given to disturbances of the motor and sensory systems that commonly occur in human beings. Throughout the text numerous references have been made to the great pioneers of the past and to present-day investigators whose contributions have added enormously to our knowledge of the subject or who have pointed the way to important advances. Perhaps the most striking change in recent years has been the application of new techniques in neurophysiology for more precise measurement and analysis of experimental results. A biophysical approach is now mandatory and some of its broad outlines have been included. This should present no difficulty to individuals interested in biological methods, especially those who wish to pursue careers in science or to become professional physiologists. With this idea in mind, I have included references to laboratory procedures and many illustrations from original research.
Table of ContentsI-Nervous Activity and Muscular Contraction.- 1. Neurophysiological Concepts and Methods.- 2. Nerve Impulses.- 3. Synaptic Transmission.- 4. Skeletal Muscle Contraction.- II-The Sense Organs.- 5. Principles of Sensory Activity.- 6. Organ of Balance.- 7. Organ of Hearing.- 8. Organ of Vision.- 9. Organs of Taste and Smell.- III-Central Nervous System.- 10. Reflex Activity.- 11. Skeletal Muscle Tone and Posture.- 12. Control of Posture.- 13. Voluntary Movement.- 14. Disturbances of Motor Functions.- 15. Somatic Sensory System.- 16. Physiology of Pain.- 17. Central Processes of Vision.- 18. Central Processes of Hearing.- 19. Disturbances of Sensory Function.- 20. Nervous Control of the VisceraAfferent System.- 21. Nervous Control of the VisceraEfferent System.- 22. Physiology of Emotion.- 23. The Prefrontal Lobes.- 24. The Reticular System.- 25. Learning and Memory.