Neurotransmitter and Dementia

Neurotransmitter and Dementia


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Neurotransmitter changes taking place in the brain of patients with dementia disorders, mainly Alzheimer type dementia, are reported. Their role in the pathogenesis of Alzheimer's disease is discussed; and the neurochemical changes are considered as a base for formulating treatment strategies. By studying markers in the cerebrospinal fluid, diagnostic methods may be achieved that will aid in diagnosing subgroups of dememtia.

Product Details

ISBN-13: 9783211821909
Publisher: Springer Vienna
Publication date: 06/29/1990
Series: Journal of Neural Transmission. Supplementa , #30
Pages: 87
Product dimensions: 8.27(w) x 10.98(h) x 0.01(d)

Table of Contents

Some effects of CNS cholinergic neurons on memory.- Subcellular distribution of acetylcholinesterase in Alzheimer’s disease: abnormal localization and solubilization.- Changes of acetylcholine and choline concentrations in cerebrospinal fluids of normal subjects and patients with dementia of Alzheimer-type.- Disturbance of the 5-hydroxytryptamine metabolism in brains from patients with Alzheimer’s dementia.- CSF ?-endorphin, HVA and 5-HIAA of dementia of the Alzheimer type and Binswanger’s disease in the elderly.- Neuropeptide levels in Alzheimer’s disease and dementia with frontotemporal degeneration.- Changes in signal transduction in Alzheimer’s disease.

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