Nicotine Replacement: A Critical Evaluation

Nicotine Replacement: A Critical Evaluation


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Nicotine Replacement: A Critical Evaluation by Ovide F Pomerleau, Cynthia S Pomerleau

Nicotine Replacement addresses the potential value and limitation of nicotine replacement techniques, with emphasis on the improvement of treatment strategies. The volume focuses on the mechanisms, efficacy, and safety and abuse potential of nicotine replacement, and includes reports that have implications for the coordination of pharmacological and behavioral therapies as well as for the overall understanding of smoking behavior.

This comprehensive volume covers a broad range of topics associated with the study of nicotine replacement. These include an examination of replacement therapies for chemical dependence, the pharmacological basis for nicotine replacement, and the roles of blood nicotine levels and upper airway stimulation in smoking. The efficacy of nicotine replacement (e.g. nicotine gum) is covered, as well as the pharmacological and behavioral factors involved in smoking relapse.

Nicotine Replacement also examines safety and abuse potential, with special attention to the toxicity of nicotine, the safety of nicotine-containing gum, and the dependence potential and abuse liability of nicotine replacement therapies.

This will be a valuable resource for physicians and other professionals involved in the treatment of smoking. The volume also offers guidelines for conducting new and critical investigations that will be useful to nicotine/smoking researchers.

Product Details

ISBN-13: 9781560242505
Publisher: Taylor & Francis
Publication date: 04/28/1992
Pages: 325
Product dimensions: 6.00(w) x 8.50(h) x 0.90(d)

Table of Contents

ContentsSection I: Mechanisms in Nicotine Replacement

  • Conceptual Basis of Replacement Therapies for Chemical Dependence
  • Pharmacologic Basis for Nicotine Replacement
  • Nicotine Replacement: The Role of Blood Nicotine Levels, Their Rate of Change, and Nicotine Tolerance
  • The Role of Upper Airway Stimulation in Smoking
  • Section II: Efficacy
  • Efficacy of Nicotine Chewing Gum: A Review
  • Dose and Nicotine Dependence as Determinants of Nicotine Gum Efficacy
  • Nicotine Replacement as Sole Therapy or as Adjunct
  • Smoking Relapse: The Role of Pharmacological and Behavioral Factors
  • Section III: Safety and Abuse Potential
  • Toxicity of Nicotine: Implications With Regard to Nicotine Replacement Therapy
  • Safety of Nicotine-Containing Gum
  • Nicotine: A Dependence-Producing Substance
  • Dependence Potential and Abuse Liability of Nicotine Replacement
  • Nicotine Replacement: An Overview

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