ISBN-10:
9048133025
ISBN-13:
9789048133024
Pub. Date:
03/15/2010
Publisher:
Springer Netherlands
Nuclear Receptors: Current Concepts and Future Challenges / Edition 1

Nuclear Receptors: Current Concepts and Future Challenges / Edition 1

by Chris M. Bunce, Moray J. Campbell

Hardcover

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Product Details

ISBN-13: 9789048133024
Publisher: Springer Netherlands
Publication date: 03/15/2010
Series: Proteins and Cell Regulation , #8
Edition description: 2010
Pages: 458
Product dimensions: 6.30(w) x 9.20(h) x 1.20(d)

Table of Contents

List of Contributors ix

1 Nuclear Receptors an Introductory Overview Chris M. Bunce Moray J. Campbell 1

2 What does Evolution Teach us about Nuclear Receptors? Gabriel Markov François Bonneton Vincent Laudet 15

3 Functions of Nuclear Receptors in Insect Development David Martin 31

4 The Glucocorticoid Receptor Robert H. Oakley John A. Cidlowski 63

5 Estrogen Receptors: Their Actions and Functional Roles in Health and Disease Stefan Nilsson Jan-Ake Gustafsson 91

6 Androgen Receptor James T. Dalton Wenqing Gao 143

7 Thyroid Hormone Receptors Björn Vennström Hong Liu Douglas Forrest 183

8 The Vitamin D Receptor (NR1I1) Orla Maguire Moray J. Campbell 203

9 Retinoic Acid Receptors Audrey Cras Fabien Guidez Christine Chomienne 237

10 PPARs: Important Regulators in Metabolism and Inflammation Linda M. Sanderson Sander Kersten 259

11 Xenobiotic Receptors CAR and PXR Curtis Klaassen Hong Lu 287

12 FXR Yandong Wang Weidong Chen Xiaosong Chen Wendong Huang 307

13 Physiological Functions of TR2 and TR4 Orphan Nuclear Receptor Su Liu Shaozhen Xie Yi-Fen Lee Chawnshang Chang 327

14 Nuclear Receptors and ATP Dependent Chromatin Remodeling: A Complex Story Craig J. Burd Trevor K. Archer 345

15 Non-Genomic Action of Sex Steroid Hormones Antimo Migliaccio Gabriella Castoria Ferdinando Auricchio 365

16 Ligand Regulation and Nuclear Receptor Action Martin Hewison 381

17 New Insights to Nuclear Receptor Gene Regulation from Analysis of their Response Elements in Target Genes Carsten Carlberg 419

18 Systems Biology: Towards Realistic and Useful Models of Molecular Networks F.J. Bruggeman A. Kolodkin K. Rybakova M. Moné H.V. Westerhoff 439

Index 455

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