The identification of occupational cancer risk factors and of carcinogens in the workplace is assuming increasing import ance in cancer epidemiology. This book, which contains the proceedings of a symposium held in Vancouver in June 1988, combines overviews by experts on substantive topics and methodologic issues of broad interest in occupational cancer epidemiology. Among the former are state of the art reviews emphasizing recent data and new and innovative analytic approaches. The substantive topics include discussion of cancer risks from exposure to complex organic mixtures, asbestos and man-made fibers, herbicides, radon, and electromagnetic fields. Risk assessment, exposure assessment, and analysis of occupa tional cohort studies are examples of the methodologic issues addressed. This book provides basic information and opens perspectives on new areas of research. In organizing our symposium we were greatly assisted by Betty Fata and Kim Rust of Venue West Conference Ltd. We appreciate the financial support received from the following: Cancer Control Agency of British Columbia Alcan Aluminium Ltd. National Health Research & Development Program Workers' Compensation Board of British Columbia Purdue Frederick Inc. Rhone-Poulenc Pharma Inc. London Drugs Ltd. Ciba-Geigy Canada Ltd. Bristol-Myers Pharmaceutical Group Schering Canada Inc. Hoffmann-La Roche Ltd. Sterling Drug Ltd. Parke-Davis Canada Inc. Beecham Laboratories Pfizer Canada Inc. Roussel Canada Inc.
Table of ContentsRole of Epidemiology in Health Risk Assessment.- Discovering Occupational Carcinogens in Population-Based Case-Control Studies: Review of Findings from an Exposure-Based Approach and a Methodologic Comparison of Alternative Data Collection Strategies.- Recent Approaches to Retrospective Exposure Assessment in Occupational Cancer Epidemiology.- Effects of Measurement Errors on Estimates of Exposure-Response Relationships.- Adjustment for Confounding in Occupational Cancer Epidemiology.- Statistical Issues in the Analysis of Data from Occupational Cohort Studies.- Towards an Automated Micronucleus Assay as an Internal Dosimeter for Carcinogen-Exposed Human Population Groups.- Human Lung Cancer Risks Due to Complex Organic Mixtures of Combustion Emissions.- Cancer Risks Due to Asbestos and Man-Made Fibres.- Herbicides and Cancer: A Review and Discussion of Methodologic Issues.- Cancer Risks from Exposure to Radon Progeny in Mines and Dwellings.- Cancer Risks Due to Exposure to Electromagnetic Fields.- Identification of Occupational Cancer Risks Using a Population-Based Cancer Registry.