Ocular Therapeutics: Eye on New Discovery focuses on emerging areas in ocular research, from new approaches to dry eye to gene therapy in the management of retinal diseases. This comprehensive book features more than 25 chapters of information that will be vital for ocular investigators and ophthalmologists bringing them new information on promising therapeutics. It is the intent of this book to provide not only information on current approaches to treatment, but also in giving the reader a greater understanding as to what may become available for treating a number of important eye diseases. Each chapter features some new aspect of treatment that holds great promise for the future. The approach has been to concentrate on those areas of ocular diseases that are more prevalent. It also features new insight for drug delivery and for managing devasting diseases, such as macula edema and glaucoma, two of the leading causes of blindness in the United States. This book will serve as an important resource as it contains a number of relevant references highlighted for their importance to the field. New investigators will be able to obtain an historical perspective for each of the topics and to develop an understanding of the new research directions that are underway. Ocular Therapeutics: Eye on New Discovery is more than a reference book, as it also provides an important glimpse into the near future.
* Contains information that is vital for ocular investigators and ophthalmologists bringing them new information on promising therapeutics.
* Provides not only information on current approaches to treatment, but also gives the reader a greater understanding as to what may become available for treating a number of important eye diseases.
* Historical perspective for each of the topics as well as an important glimpse into the near future to develop an understanding of the new research directions underway.
* New insight for drug delivery and for managing devastating diseases, such as macula edema and glaucoma, two of the leading causes of blindness in the United States
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Table of ContentsSection I - General Principles and Therapeutic Targets
Chapter 1: The Eye as Drug Target: Overview
Chapter 2: Drug Delivery Systems in Ophthalmic Applications
Chapter 3: IOP as a Target - Inflow and Outflow Pathways
Chapter 4: The ciliary body: a potential multifaceted functional neuroendocrine unit.
Chapter 5: Growth Factors and Neurotrophic Factors as Targets
Section II. Visual Pathway
Chapter 6: New therapies for Dry Eye Disease
Chapter 7: Refractive Surgery: Corneal Opacity (haze) after Surface Ablation
Chapter 8: Progress in Preventing Age-Related Cataract
Chapter 9: Myopia Pharmacology: Etiologic Clues, Therapeutic Potential
Section III. Inflammation, Immune System and Anti-infectives
Chapter 10: Immune system and the eye
Chapter 11: Ocular Allergy: Clinical, Therapeutic and Drug Discovery Considerations
Chapter 12: Ocular Inflammation in Anterior Segment
Chapter 13: Posterior Segment uveitis
Chapter 14: New Anti-Infectives for Ophthalmology
Section IV. Clinical Therapeutics
Chapter 15: Tissue Repair and Regeneration
Chapter 16: Therapeutic Drugs for Anterior Segment Ocular Surgery
Chapter 17: Therapeutic Drugs for Posterior Segment Vitrectomy Surgery
Chapter 18: Progress and Prospects in Ocular Gene Therapy
Section V. Retinal Diseases and Neuropathies
Chapter 19: Neuroprotection in Glaucoma
Chapter 20: Degenerative Retinopathies
Chapter 22: Ocular Angiogenesis