The past two years have taken their toll on Callie St. Pierre. First she loses her son, then the divorce-well who could blame her for being an emotional wreck? But lately she's been handling unexpected changes pretty well. Maybe the story of Catherine, a troubled nurse from the past, has inspired her. Or more likely it's the encouragement of family and friends that has Callie looking forward to her future. So when a killer hurricane heads directly for New Orleans, she feels confident that she can manage whatever happens. But nobody is prepared for this one! She and her hospital colleagues soon sense a growing desperation as they wait to be rescued, realizing that help is not coming anytime soon. Now facing unimaginable challenges and choices, Callie wonders if she's strong enough to survive this nightmare. It's a question that has long tormented her. Finally, she'll know the answer.