The dynamic field of flavin and flavoprotein biochemistry has seen rapid advancement in recent years. This comprehensive two volume set provides an overview of all aspects of contemporary research in this important class of enzymes. Topics treated include flavoproteins involved in energy generation, signal transduction and electron transfer (including respiration); oxygen activation by flavoproteins; the biology and biochemistry of complex flavoproteins; flavin and flavoprotein photochemistry/photophysics as well as biotechnological applications of flavoproteins. Recent developments in this field include new structures (including those of large membrane-integral electron transfer complexes containing FMN or FAD), elucidation of the role of flavoproteins in cell signalling pathways (including both phototaxis and the circadian cycle) and important new insights into the reaction mechanisms of flavin-containing enzymes. This volume focussing on oxidases, dehydrogenases and related systems is an essential reference for all researchers in biochemistry, chemistry, photochemistry and photophysics working on flavoenzymes.
|Product dimensions:||6.69(w) x 9.45(h) x (d)|
|Age Range:||18 Years|
About the Author
Russ Hille, University of California, Riverside, CA, USA; Susan Miller, University of California, San Francisco, CA, USA; Bruce Palfey, University of Michigan, Ann Arbor, MI, USA.
Table of Contents
I. Flavoproteins in Energy GenerationA. NADH dehydrogenaseB. Acyl-CoA dehydrogenasesC. Electron-transferring flavoproteinD. Lipoamide dehydrogenase, glutathione reductase and other transhydrogenasesE. Succinate Dehydrogenase and fumarate reductaseF. Ferredoxin:NADP+ oxidoreductaseII. Complex FlavoproteinsA. Nitrate reductasesB. Xanthine oxidoreductase and related enzymesC. Phthalate dioxygenase reductaseD. Cytochrome P-450 reductaseE. Flavocytochrome b2III. Oxygen Activation by FlavoproteinsA. D-amino acid oxidase and related enzymesB. Cholesterol oxidaseC. Flavin monooxygenasesD. NitroreductasesIV. Flavin Amine OxidasesA. Monoamine oxidasesB. Trimethylamine and dimethylamine dehydrogenasesC. Histone-lysine demethylasesV. Flavoproteins and LightA. DNA photolyaseB. Plant blue-light receptorC. Flavoproteins of the Circadian cycleD. Luciferase and related systemsVI. The Chemistry of FlavinsA. Oxidation-reduction and electron transfer chemistryB. Covalent modification of flavoproteinsC. Unconventional flavins in chemsitry and biologyD. Photophysics of flavins