Pub. Date:
Springer-Verlag New York, LLC
Patch-Clamp Methods and Protocols / Edition 1

Patch-Clamp Methods and Protocols / Edition 1

by Peter Molnar, James J. Hickman


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Product Details

ISBN-13: 9781588296986
Publisher: Springer-Verlag New York, LLC
Publication date: 09/19/2007
Series: Methods in Molecular Biology , #403
Edition description: 2007
Pages: 321
Product dimensions: 5.98(w) x 9.02(h) x 0.04(d)

Table of Contents

Table of contents

Part 1. Pharmacology

1. Pharmacological analysis of recombinant NR1a/2A and NR1a/2B NMDA
receptors using whole-cell patch clamp method. Laszlo Fodor and Jozsef
2. Memantine as an example of a fast, voltage-dependent, open channel
N-methyl-D-aspartate (NMDA) receptor blocker. Chris G. Parsons and Kate
3. Methods for evaluation of positive allosteric modulators of glutamate AMPA receptors. Edward R. Siuda, Jennifer C. Quirk and Eric
S. Nisenbaum
4. Automated voltage clamp technique. Andrea Ghetti, Antonio Guia and
Jia Xu
5. Flip-the-Tip: automated patch clamping based on glass electrodes.
Michael Fejtl, Uwe Czubayko, Alexander Hümmer, Tobias Krauter and
Albrecht Lepple-Wienhues
6. The Roboocyte: Automated Electrophysiology Based on Xenopus Oocytes.
Christine Leisgen, Mike Kuester and Christoph Methfessel

Part 2. Physiology

7. Infrared guided laser stimulation as a tool for elucidating the synaptic site of expression of long-term synaptic plasticity. Gerhard
Rammes, Mathias Eder, Walter Zieglgänsberger and Hans-Ulrich Dodt
8. Single-cell RT-PCR, a Technique to Decipher the Electrical,
Anatomical and Genetic Determinants of Neuronal Diversity. Maria
Toledo-Rodriguez and Henry Markram
9. Mechanosensitive Ion Channels investigated simultaneously by
Scanning Probe Microscopy and Patch clamp. Matthias G. Langer
10. Synaptic Connectivity in Engineered Neuronal Networks. Peter
Molnar, Jung-Fong Kang, Neelima Bhargava, Mainak Das and James J.
11. Modeling of Action Potential Generation in NG108-15 Cells. Peter
Molnar and James J. Hickman
12. Whole-cell Voltage-clamp on Skeletal Muscle Fibers with the
Silicone-Clamp Technique. Sandrine Pouvreau, Claude Collet, Bruno
Allard and Vincent Jacquemond
13. Determination of channel properties at the unitary level in adult mammalian isolated cardiomyocytes. RomainGuinamard
14. Electrophysiological Properties of Embryonic Stem Cells During
Differentiation into Cardiomyocyte-like Cell Types. Antoni C.G. van
Ginneken and Arnoud. C. Fijnvandraat
15. Hybrid Neuronal Network Studies Under Dynamic Clamp. Alan D. Dorval
II, Jonathan Bettencourt, Theoden I. Netoff and John A. White
16. Cardiac channelopathies studied with the dynamic action potential clamp technique. Géza Berecki, Jan G. Zegers, Ronald Wilders and Antoni
C.G. van Ginneken

Part 3. Biophysics

17. Principles of Single-Channel Kinetic Analysis. Feng Qin *
Theoretical chapter
18. Use of Xenopus oocytes to measure ionic selectivity of pore-forming peptides and ion channels. Thierry Cens and Pierre Charnet
19. Estimation of quantal parameters with multiple-probability fluctuation analysis. Chiara Saviane and Robin Angus Silver

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