Pathophysiology of Disease: An Introduction to Clinical Medicine 7/E / Edition 7

Pathophysiology of Disease: An Introduction to Clinical Medicine 7/E / Edition 7

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McGraw-Hill Professional Publishing
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Pathophysiology of Disease: An Introduction to Clinical Medicine 7/E / Edition 7

A full-color, case-based review of the essentials of pathophysiology—covering all major organs and systems

The goal of this trusted text is to introduce you to clinical medicine by reviewing the pathophysiologic basis of 120 diseases (and associated signs and symptoms) commonly encountered in medical practice. The authors, all experts in their respective fields, have provided a concise review of relevant normal structure and function of each body system, followed by a description of the pathophysiologic mechanisms that underlie several common diseases related to that system.

Each chapter of Pathophysiology of Disease concludes with a collection of case studies and questions designed to test your understanding of the pathophysiology of each clinical entity discussed. These case studies allow you to apply your knowledge to specific clinical situations. Detailed answers to each case study question are provided at the end of the book. This unique interweaving of physiological and pathological concepts will put you on the path toward thinking about signs and symptoms in terms of their pathophysiologic basis, giving you an understanding of the "why" behind illness and treatment.


  • 120 case studies (9 new) provide an opportunity for you to test your understanding of the pathophysiology of each clinical entity discussed
  • Checkpoint questions provide review and appear in every chapter
  • Updates and revisions throughout this new edition reflect the latest research and developments
  • Numerous tables and diagrams encapsulate important information
  • Updated references for each chapter topic

Pathophysiology of Disease is a true must-have resource for medical students preparing for the USMLE
Step 1 exam, as well as students engaged in their clerkship studies. House officers, nurses, nurse practitioners, physicians’ assistants, and allied health practitioners will find its concise presentation and broad scope a great help in facilitating their understanding of common disease entities.

Product Details

ISBN-13: 9780071806008
Publisher: McGraw-Hill Professional Publishing
Publication date: 04/30/2014
Pages: 784
Sales rank: 41,283
Product dimensions: 8.40(w) x 10.80(h) x 1.00(d)

Table of Contents

Key Features Authors Preface
1. Introduction, Stephen J. McPhee and Gary D. Hammer
2. Genetic Disease, Gregory Barsh
3. Disorders of the Immune System, Jeffrey L. Kishiyama
4. Infectious Diseases, Karen C. Bloch
5. Neoplasia, Mark M. Moasser
6. Blood Disorders, J. Ben Davoren and Sunny Wang
7. Nervous System Disorders, Catherine Lomen-Hoerth and Robert O. Messing
8. Diseases of the Skin, Timothy H. McCalmont
9. Pulmonary Disease, Thomas J. Prendergast, Stephen J. Ruoss, and Eric J. Seeley
10. Cardiovascular Disorders: Heart Disease, Fred M. Kusumoto
11. Cardiovascular Disorders: Vascular Disease, Igor Mitrovic
12. Disorders of the Adrenal Medulla, Tobias Else, Gary D. Hammer, and Stephen J. McPhee
13. Gastrointestinal Disease, Jason C. Mills, Thaddeus S. Stappenbeck, and Nigel Bunnett
14. Liver Disease, Mandana Khalili, Charles E. Liao, and Tung T. Nguyen
15. Disorders of the Exocrine Pancreas, Christopher J. Sonnenday, Diane M. Simeone, and Stephen J. McPhee
16. Renal Disease, Benjamin D. Parker and Joachim H. Ix
17. Disorders of the Parathyroids & Calcium & Phosphorus Metabolism, Dolores M. Shoback and Deborah E. Sellmeyer
18. Disorders of the Endocrine Pancreas, Janet L. Funk
19. Disorders of the Hypothalamus & Pituitary Gland, Tobias Else and Gary D. Hammer
20. Thyroid Disease, Douglas C. Bauer and Stephen J. McPhee
21. Disorders of the Adrenal Cortex, Tobias Else, Gary D. Hammer, and Stephen J. McPhee
22. Disorders of the Female Reproductive Tract, Karen J. Purcell and Robert N. Taylor
23. Disorders of the Male Reproductive Tract, Mikkel Fode, Jens Sonksen, Stephen J. McPhee, and Dana A. Ohl
24. Inflammatory Rheumatic Diseases, Allan C. Gelber, Stuart M. Levine, and Antony Rosen
25. Case Study Answers, Yeong Kwok, Eva M. Aagaard, and Jonathan D. Fuchs
Subject Index

Stephen J. McPhee, MD

Professor of Medicine

Division of General Internal Medicine

Department of Medicine

University of California, San Francisco

San Francisco, CA

Gary D. Hammer, MD, PhD

Millie Schembechler Professor of Adrenal Cancer

Director, Endocrine Oncology Program

Comprehensive Cancer Center

University of Michigan

Ann Arbor, MI

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