ISBN-10:
1617379212
ISBN-13:
9781617379215
Pub. Date:
11/09/2010
Publisher:
Springer-Verlag New York, LLC
Pharmacogenomics and Personalized Medicine / Edition 1

Pharmacogenomics and Personalized Medicine / Edition 1

by Nadine Cohen

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Product Details

ISBN-13: 9781617379215
Publisher: Springer-Verlag New York, LLC
Publication date: 11/09/2010
Series: Methods in Pharmacology and Toxicology
Edition description: Softcover reprint of hardcover 1st ed. 2008
Pages: 509
Product dimensions: 6.10(w) x 9.25(h) x 0.04(d)

Table of Contents

Preface Contributors Challenges, Opportunities and Evolving Landscape in Pharmacogenomics and Personalized Medicine: An Industry Perspective
Nadine Cohen and Theresa Frangiosa Considerations for Sample Collections Intended for Pharmacogenomic analyses: The Pharmacogenomics protocol and informed consent form
Deborah Ricci and Monique Franc Pharmacogenomics: The Regulatory Environment and Labeling Implication
Myong-Jin Kim, Shiew-Mei Huang, Atiqur Rahman, Felix W. Frueh,
Lawrence J. Lesko Applications of Pharmacogenomics in Drug Discovery
Duncan McHale Applications of Pharmacogenomics in Clinical Trials
Monique Franc Pharmacogenomics applications in drug metabolism: from genotyping to drug label-challenges?
Ann K. Daly The Genetics of Adverse Drug Reactions – Promises and Problems
Martin Armstrong Strategies and resources for marker selection and genotyping in genetic association studies
Nicole Soranzo, Dong-Jing Fu and Qingqin S. Li Study Design and Statistical Methods in Pharmacogenomics Research: From
Candidate Genes to Genome Wide Screens
Nicholas J. Schork, Nathalie Malo, Eric J. Topol
Holy SNP, Batman!
Reyna Favis Use of Predictive Biomarker Classifiers in the Design of Pivotal Clinical
Trials
Richard Simon Translation of biomarkers into clinical utility
William Trepicchio and George Mulligan Pharmacogenomic Study Feasibility Assessment and Pharmaceutical Business
Decision-Making
Monique Franc and Theresa Frangiosa Co-development of drugs andPharmacogenomics based Diagnostics in Oncology Jeffrey Ross Pharmacogenomics applications in Epilepsy
Chantal Depondt Pharmacogenomics in Alzheimer’s Disease
Ramon Cacabelos Pharmacogenomics applications in Psychiatric disorders
Todd Lencz and Anil K. Malhotra Pharmacogenomics in HIV Disease
Amalio Telenti Pharmacogenomics and Cardiovascular Drugs
Gérard Siest, Hind Berrahmoune, Jean-Brice Marteau,
and Sophie Visvikis-Siest
Pharmacogenomic applications in Children
Struan F.A. Grant and Hakon Hakonarson Pharmacogenomics of rare and monogenic disorders
Paul Maher

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