The physiology and pathology of membrane (contact or surface) digestion of the three main components of the food of animals and man is a rapidly developing field, and there is little doubt that newer ob servations will become available as time progresses. As the dis coverer of the phenomenon of membrane digestion, Professor Ugolev is well aware of the relative infancy of this subject, and in presenting the book at this time his primary purpose was to acquaint the reader with the experimental basis for the observed phenomenon and to stimulate interest in the further work required for the elucidation of details and for proper orientation. Translations as means of communication of ideas and experimental facts are of obvious importance and they require no apologies or explanations, particularly to those who are engaged in scientific endeavors. In making this book available to those who find the Russian language an insurmountable barrier, our main efforts were directed toward preserving the author's meaning, spirit, and intent as accurately as possible. It is hoped that this objective has been attained, and that the minor unintentional errors will be forgiven by the reader and by the author. The translator wishes to express to Professor Ugolev, whom he met in Leningrad in 1965, his appreciation for the trust in the ability of the translator to make Professor Ugolev's labor oflove, the present book, available in the English language.
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Table of ContentsI Basic Types of Digestion and Their Classification.- II Digestive Processes in the Small Intestines of Higher Animals The Role of Membrane Digestion.- Hydrolysis of Polysaccharides.- Hydrolysis of Oligosaccharides.- Hydrolysis of Proteins and Large Peptides.- Hydrolysis of Oligopeptides.- Hydrolysis of Fatty Acid Esters.- Hydrolysis of Phosphoric Acid Esters.- Criteria Employed in the Investigation of Localization of Digestive Processes.- Differentiation of Distal Extracellular Digestion from Cellular Digestion (Intracellular and Membrane).- Differentiation of Membrane from Intracellular Digestion..- III Physicochemical and Structural Aspects of Membrane Digestion.- IV Detailed Characterization of Membrane Digestion in Higher Animals.- Interrelationships of Cavital and Membrane Digestion.- Desquamation of the Intestinal Epithelium and Enzymatic Hydrolysis in the Cavity of the Small Intestine.- The Effect of Membrane Digestion on the Initial States of the Hydrolysis of Polymers.- Topography of Membrane Digestion.- Sterility of Membrane Digestion.- Peristalsis of the Intestinal Tract and Membrane Digestion..- Enzymatic Layer of the Intestinal Surface.- Membrane Digestion and Absorption.- Regulation of Membrane Digestion.- V Membrane Digestion and the Pathology of the Gastrointestinal Tract.- Methods of Investigating the Digestive Functions of the Intestinal Epithelium.- The Alteration of Structure and Ultrastructure of the Intestinal Surface.- Alteration in the Composition and Structure of the Enzymatic Layer of the Intestinal Surface.- Membrane Digestion During Irradiation Damage.- Compensatory Reactions.- VI Evolutionary Aspects of Membrane Digestion.- Membrane Digestion in Ontogenesis.- Regarding the Comparative Physiology of Membrane Digestion.- The Origin of Digestion The Origin of Membrane Digestion.- Conclusion.- Supplementary Information.