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Plants That Fight Cancer
     

Plants That Fight Cancer

by Spiridon E. Kintzios, Maria Barberaki, Maria G. Barberaki
 

ISBN-10: 0415298539

ISBN-13: 9780415298537

Pub. Date: 01/15/2004

Publisher: Taylor & Francis

Plants that Fight Cancer is an up-to-date, extensive review of plant genera and species with documented anticancer properties, serving as an invaluable aid to those engaged in cancer therapy or research. Current knowledge is briefly described in the first part of the book, along with the conventional, advanced and alternative treatments for cancer. This is followed

Overview

Plants that Fight Cancer is an up-to-date, extensive review of plant genera and species with documented anticancer properties, serving as an invaluable aid to those engaged in cancer therapy or research. Current knowledge is briefly described in the first part of the book, along with the conventional, advanced and alternative treatments for cancer. This is followed by a general review of plant-derived groups of compounds with anticancer properties (chemistry, biosynthesis, mode of action). In the third section, more than 150 terrestrial plant genera and species are examined, including the tradition and mythology of each, along with their distribution, botany, culture, active ingredients and product applications, as well as an analysis of expected results and risks. Photographs and illustrations of each species are also included. The book closes with an analysis of algal extracts and isolated metabolites with anticancer activity. A summary of published research for each species and the chemical structures of the most important compounds are provided as background information for the expert reader.

Product Details

ISBN-13:
9780415298537
Publisher:
Taylor & Francis
Publication date:
01/15/2004
Pages:
312
Product dimensions:
6.90(w) x 10.10(h) x 1.00(d)

Table of Contents

PART I: WHAT DO WE KNOW ABOUT CANCER AND ITS THERAPY?
Incidence and Causes
Classification of Cancer Types
Therapy
Conventional Cancer Treatments
Advanced Cancer Treatments
Other Advanced Therapies
Alternative Cancer Treatments
From Source to Patient: Testing the Efficiency of a Candidate Anticancer Drug
Preclinical Tests
Phases of Clinical Trials
Clinical Trial Protocols
PART II: PLANTS AND CANCER
Brief Overview of the General Organization of the Plant Cell
The Chemical Constituents of the Plant Cell
Primary Metabolites
Secondary Metabolites
Why Do Plant Compounds Have an Anticancer Activity?
Chemical Groups of Natural Products with Anticancer Properties
Alkaloids
Polysaccharides
Glycosides
Lipids (Saponifiable)
Flavonoids
Proteins
Annonaceous Acetogenins
Terpenoids
Nucleic Acids
Lignans
Phenols and Derivatives
Aldehydes
Unsaponifiable Lipids
Unidentified Compounds
Biotechnology and the Supply Issue
PART III: TERRESTRIAL PLANT SPECIES WITH ANTICANCER ACTIVITY: A PRESENTATION
Introduction: General Botanical Issues
Species-specific Information
The Guardian Angels: Plant Species Used in Contemporary Clinical Cancer Treatment
Promising Candidates for the Future: Plant Species with a Laboratory-Proven Potential
The Fable: Where Tradition Fails to Meet Reality
Other Species with Documented Anticancer Activities
PART IV: CYTOTOXIC METABOLITES FROM MARINE ALGAE
Introduction
Cytotoxic Metabolites from Chlorophyta
Cytotoxic Metabolites from Rhodophyta
Cytotoxic Metabolites from Phaeophyta
Cytotoxic Metabolites from Microalgae
Conclusions
References
APPENDIX: CHEMICAL STRUCTURES OF SELECTED COMPOUNDS
References
Chemical Index
Species Index

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