Population Epigenetics: Methods and Protocols

Population Epigenetics: Methods and Protocols

Paperback(Softcover reprint of the original 1st ed. 2017)

$159.99
View All Available Formats & Editions
Eligible for FREE SHIPPING
  • Want it by Wednesday, October 24?   Order by 12:00 PM Eastern and choose Expedited Shipping at checkout.

Overview

Population Epigenetics: Methods and Protocols by Paul Haggarty

This detailed volume focuses on population epigenetics, which is of increasing interest to policy makers searching for explanations for complex epidemiological observations and conceptual models on which to base interventions. With a concentration on DNA methylation, the emphasis is on the most commonly studied epigenetic phenomenon that is most amenable to further study. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Population Epigenetics: Methods and Protocols aims to aid population researchers in exploiting the latest insights into epigenetics to improve our understanding of the factors that influence human health and longevity.

Product Details

ISBN-13: 9781493983339
Publisher: Springer New York
Publication date: 07/12/2018
Series: Methods in Molecular Biology , #1589
Edition description: Softcover reprint of the original 1st ed. 2017
Pages: 206
Product dimensions: 7.01(w) x 10.00(h) x (d)

Table of Contents

1. Library Construction for High-Throughput Mobile Element Identification and Genotyping


Hongseok Ha, Nan Wang, and Jinchuan Xing




2. The Design and Optimization of DNA Methylation Pyrosequencing Assays Targeting Region-Specific Repeat Elements


Gwen Hoad and Kristina Harrison



3. Determining Epigenetic Targets: A Beginner’s Guide to Identifying Genome Functionality Through Database Analysis


Elizabeth A. Hay, Philip Cowie, and Alasdair MacKenzie



4. Detecting Spatial Chromatin Organization by Chromosome Conformation Capture II: Genome-Wide Profiling by Hi-C


Matteo Vietri Rudan, Suzana Hadjur, and Tom Sexton



5. Quantitative Analysis of Intra-chromosomal Contacts: The 3C-qPCR Method


Vuthy Ea, Franck Court, and Thierry Forne



6. 5-Hydroxymethylcytosine Profiling in Human DNA


John P. Thomson, Colm E. Nestor, and Richard R. Meehan



7. Adjusting for Cell Type Composition in DNA Methylation Data Using a Regression-Based Approach



Meaghan J. Jones, Sumaiya A. Islam, Rachel D. Edgar, and Michael S. Kobor



8. Correcting for Sample Heterogeneity in Methylome-Wide Association Studies



James Y. Zou



9. Nano-MeDIP-seq Methylome Analysis Using Low DNA Concentrations


Lee M. Butcher and Stephan Beck



10. Bisulfite Conversion of DNA from Tissues, Cell Lines, Buffy Coat, FFPE Tissues, Microdissected Cells, Swabs, Sputum, Aspirates, Lavages, Effusions, Plasma, Serum, and Urine


Maria Jung, Barbara Uhl, Glen Kristiansen, and Dimo Dietrich



11. Analysis of Imprinted Gene Regulation


David A. Skaar and Randy L. Jirtle



12. Statistical Methods for Methylation Data


Graham W Horgan and Sok-Peng Chua

Customer Reviews

Most Helpful Customer Reviews

See All Customer Reviews