ISBN-10:
0801880092
ISBN-13:
9780801880094
Pub. Date:
08/06/2004
Publisher:
Johns Hopkins University Press
Population Genetics: A Concise Guide / Edition 2

Population Genetics: A Concise Guide / Edition 2

by John H. Gillespie

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Overview

Population Genetics: A Concise Guide / Edition 2

This concise introduction offers students and researchers an overview of the discipline that connects genetics and evolution. Addressing the theories behind population genetics and relevant empirical evidence, John Gillespie discusses genetic drift, natural selection, nonrandom mating, quantitative genetics, and the evolutionary advantage of sex. First published to wide acclaim in 1998, this brilliant primer has been updated to include new sections on molecular evolution, genetic drift, genetic load, the stationary distribution, and two-locus dynamics. This book is indispensable for students working in a laboratory setting or studying free-ranging populations.

Product Details

ISBN-13: 9780801880094
Publisher: Johns Hopkins University Press
Publication date: 08/06/2004
Edition description: second edition
Pages: 232
Product dimensions: 6.00(w) x 9.00(h) x 0.61(d)
Age Range: 18 Years

About the Author

John H. Gillespie is a professor of evolution at the University of California, Davis.

Table of Contents

List of Figuresix
Prefacexi
1Genetic Variation1
1.1DNA variation in Drosophila2
1.2Loci and alleles6
1.3Genotype and allele frequencies10
1.4The Hardy-Weinberg law12
1.5Answers to problems18
2Genetic Drift21
2.1A first look at genetic drift22
2.2The decay of heterozygosity25
2.3Mutation and drift29
2.4Molecular evolution32
2.5The neutral theory36
2.6The coalescent40
2.7The effective size of a population47
2.8Another model of genetic drift49
2.9The stationary distribution53
2.10Is genetic drift important in evolution?55
2.11Answers to problems56
3Natural Selection59
3.1The fundamental model61
3.2Relative fitness62
3.3Three kinds of selection64
3.4Mutation-selection balance70
3.5Genetic load71
3.6The heterozygous effects of alleles76
3.7Changing environments85
3.8The stationary distribution90
3.9Selection and drift91
3.10Molecular evolution95
3.11Answers to problems98
4Two-Locus Dynamics101
4.1Linkage disequilibrium101
4.2Two-locus selection105
4.3Genetic draft111
4.4Answers to problems116
5Nonrandom Mating119
5.1Generalized Hardy-Weinberg120
5.2Identity by descent121
5.3Inbreeding123
5.4The evolution of selfing127
5.5Subdivision131
5.6Answers to problems136
6Quantitative Genetics139
6.1Correlation between relatives139
6.2Response to selection150
6.3Evolutionary quantitative genetics154
6.4Dominance160
6.5The intensity of selection166
6.6Answers to problems168
7The Evolutionary Advantage of Sex169
7.1Genetic segregation170
7.2Crossing-over173
7.3Muller's ratchet174
7.4Kondrashov's hatchet179
7.5Answers to problems183
Appendix AMathematical Necessities185
Appendix BProbability189
Bibliography207
Index211

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Population Genetics: A Concise Guide 1 out of 5 based on 0 ratings. 1 reviews.
Anonymous More than 1 year ago
This is a classic book in population genetics for a reason. It is excellent and I highly recommend it. But this ebook version is unuseable. Throughout the text, Gillespie uses two symbols, a normal letter H and a curly H. They are sometimes interchangeable in equations, but not always, and understanding the difference is clearly vital. However in the ebook, the curly H is written as a normal H. This is incredibly confusing and makes the book completely useless. Buy a hard copy, the ebook is awful.