Prescribed Medications and the Public Health: Laying the Foundation for Risk Reduction

Prescribed Medications and the Public Health: Laying the Foundation for Risk Reduction

by William N. Kelly


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An alarming look at America's other drug problem-medication safety! Drug misadventures are an all-too-frequent and deadly cause of adverse medical events. Prescribed Medications and the Public Health: Laying the Foundation for Risk Reduction explores ways to combat the widespread problem of adverse drug events (ADEs). This comprehensive book shows how our broken health care and medication use system often inflicts harm-most of it preventable-on patients. Strategies are presented to help health care managers, health professionals, regulators, and policymakers to dynamically improve the entire system. With the growing use of prescribed medications comes a rising number of adverse drug reactions, drug interactions, allergic reactions, and medication errors. Prescribed Medications and the Public Health discusses problems such as drug supply issues, drug defects, counterfeit drugs, limitations for oversight of Internet prescriptions, inaccurate splitting of pills, and poor administration of drugs. The book examines the issues from all angles, including patient considerations, drug factors, and unsafe practices that contribute to ADEs. Liability costs for drug injury are reviewed, along with effective practical strategies for preventing, reducing, detecting, and documenting adverse drug events. National and local plans are explored to help achieve the essential goal of greater safety throughout the system. The text is extensively referenced and includes numerous figures and tables to clearly present information.

Product Details

ISBN-13: 9780789023612
Publisher: Taylor & Francis
Publication date: 01/28/2005
Edition description: 1ST
Pages: 355
Product dimensions: 5.90(w) x 8.30(h) x 1.00(d)

Table of Contents

  • Foreword (David W. Bates)
  • Preface
  • Acknowledgments
  • Chapter 1. America’s Drug Problems
  • America’s "Other" Drug Problem
  • Drug Misadventures
  • The Medication Use System
  • Drug Supply Problems
  • Poor Prescribing, Dispensing, and Administration of Drugs
  • Poor Patient Communication
  • Drug Companies’ Contributions to the Problem
  • A Broken Part of a Larger Broken System
  • Summary
  • Chapter 2. The Nature and Scope of the Medication Safety Problem
  • The Nature of the Problem
  • The Scope of the Problem
  • Adverse Drug Event Severity
  • Cost of the Problem
  • Drugs Commonly Associated with Adverse Drug Events
  • Summary
  • Chapter 3. How Medication Harms Patients
  • Patient Factors That Contribute to Adverse Drug Events
  • Drug Factors That Contribute to Adverse Drug Events
  • Unsafe Practices That Contribute to Adverse Drug Events
  • Why Unsafe Medication Practices Happen
  • Predicting Who Makes Medication Errors
  • Managing Behavior to Reduce Medication Errors
  • Blaming Health Professionals for Errors
  • Adverse Drug Events Due to Host-Drug Interaction
  • What Is Preventable?
  • Solutions to Preventing Adverse Drug Events
  • Summary
  • Chapter 4. The Problem of Adverse Drug Reactions
  • Definitions
  • Types of Adverse Drug Reactions
  • Case Examples
  • Recognizing and Reporting Adverse Drug Reactions
  • Epidemiology of Adverse Drug Reactions
  • Poor Practices That Contribute to Adverse Drug Reactions
  • Black-Box Warnings
  • Recognizing and Assessing Adverse Drug Reactions
  • Harmonizing Definitions
  • Treatment
  • Summary
  • Chapter 5. Dangerous Allergic Drug Reactions
  • Definitions
  • Types of Allergic Drug Reactions
  • Case Examples
  • Recognition
  • Epidemiology
  • Poor Practices
  • Treatment
  • Prevention
  • Summary
  • Chapter 6. Are Drug Interactions Really Dangerous?
  • Definitions
  • Case Examples
  • How Drug Interactions Happen
  • Epidemiology
  • Cost
  • Prevention
  • Detecting Harmful Drug Interactions Is Not So Easy
  • The Pharmacist’s Duty to Warn
  • Which Drug Interactions Are the Most Harmful?
  • Treatment
  • Patient Education
  • Summary
  • Chapter 7. The Most Dangerous Drug Misadventure
  • Background
  • Definitions
  • Error Classification
  • Case Examples
  • Epidemiology
  • Patients
  • Cost
  • What Is the Problem?
  • Common Types of Medication Errors
  • Sentinel Events
  • Major Causes of Medication Error
  • Summary
  • Chapter 8. Are Vaccines Safe?
  • Benefits versus Risks
  • Evaluation of Risk
  • Severity of Adverse Vaccine Events
  • Assessing Whether a Vaccine Is the Cause of an Adverse Event
  • Vaccine Injury Compensation
  • Emotion versus Science
  • Current Vaccine Safety Controversies
  • Etiology of Adverse Vaccine Events
  • Lessons Learned: Changes That Are Needed
  • Summary
  • Chapter 9. Probing the Ambulatory Frontier
  • Ambulatory Care
  • Epidemiology
  • Medication Risks in the Ambulatory Environment
  • Some Solutions
  • Summary
  • Chapter 10. The Liability for Drug Injury
  • Drug Injury Outcomes
  • Case Examples
  • Preventability
  • Blame
  • Remedies
  • Medical Malpractice Claims for Drug Injury
  • The Role of Expert Testimony in Drug Injury Claims
  • Claims, Verdicts, and Settlements for Drug Injury
  • Risk Management
  • Summary
  • Chapter 11. Assessing the Evidence of Drug Injury
  • Finding Supporting Evidence on "Can It Happen?"
  • Evidence-Based Medicine Studies
  • Did the Drug Cause the Adverse Event?
  • How Did It Occur?
  • Gaps Between What Is Known and Practice
  • Summary
  • Chapter 12. Detecting and Documenting Adverse Drug Events
  • Retrospective Methods of Detecting ADEs
  • Concurrent Methods of Detecting Adverse Drug Events
  • Comparing the Various Ways to Detect Adverse Drug Events
  • Innovative Methods of Detecting Adverse Drug Events
  • Documenting Adverse Drug Events
  • Summary
  • Chapter 13. Investigating, Assessing, and Reporting Adverse Drug Events
  • Investigating Adverse Drug Events
  • Assessing Adverse Drug Events
  • Reporting Adverse Drug Events
  • Other Reporting Methods
  • Comparing Medication Error Rates
  • Deficiencies in Reporting Adverse Drug Events
  • Summary
  • Chapter 14. Can Serious Adverse Drug Events Be Predicted?
  • What Causes Adverse Drug Effects?
  • The Current State of Computerized Medication-Use Systems
  • The Ideal Adverse Drug Event System
  • Identifying Risks for Adverse Drug Events
  • Potential Risk Factors for Adverse Drug Events
  • Predicting Adverse Drug Events
  • Building a Model
  • Application of Risk Model
  • Genomics
  • Summary
  • Chapter 15. Preventing and Reducing Medication Injury
  • What Is the Goal?
  • Evidence-Based Safe Medication Practices
  • Best Practices to Improve Medication Safety
  • Innovative Practices to Improve Medication Safety
  • Summary
  • Chapter 16. What’s a Patient to Do?
  • Patient Needs
  • Fulfilling Patients’ Needs
  • Patient and Practitioner Education
  • Tips for Patients
  • Tips for Practitioners
  • Summary
  • Chapter 17. Developing National and Local Plans to Improve Medication Safety
  • The National Landscape for Improving Medication Safety
  • Progress Since the First IOM Report
  • Local Plans to Improve Medication Safety
  • Tools for Improving Medication Safety
  • Summary
  • Chapter 18. Improving Medication Safety: Pursuing Optimization or Perpetuating Illusions?
  • Some Macro Issues and Proposed Solutions
  • Is Progress Being Made?
  • Pockets of Resistance
  • What Is Needed?
  • Summary
  • Notes
  • Index

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