Progress in Parkinson Research

Progress in Parkinson Research


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Product Details

ISBN-13: 9781461280682
Publisher: Springer US
Publication date: 09/17/2011
Edition description: 1988
Pages: 228
Product dimensions: 6.69(w) x 9.61(h) x 0.02(d)

Table of Contents

1. The Current Clinical Picture of Parkinson’s Disease.- 2. The Neuropathology of Parkinson’s Disease.- 3. Anatomical and Pharmacological Comparisons between Dopamine D1 and D2 Receptors in Mammalian CNS.- 4. Architecture of Cholinergic Pre- and Postsynaptic Markers in the Primate Striatum.- 5. Functional Anatomy of Dopamine Receptors.- 6. New Insights into the Regulation of Dopamine Receptor Subtypes and Their Roles in Behavior.- 7. Dopamine Receptors and Signal Transduction.- 8. The Therapeutic Potential of D1 and D2 Dopamine Agonists in Parkinson’s Disease.- 9. Isolation and Biochemical Characterization of the D1 and D2 Dopamine Receptors.- 10. MPTP: Twenty Questions.- 11. Search for Environment or Endogenous Neurotoxins Related to MPTP.- 12. MPTP Neurotoxicity and the “Biochemical” Blood-Brain Barrier.- 13. Biochemistry of the Neurotoxic Action of MPTP and What It May Teach Us about Etiology of Idiopathic Parkinsonism.- 14. A Biological Evaluation of Some 2’-Substituted Analogs of MPTP.- 15. Hydrogen Peroxide Production in Dopamine Neurons: Implications for Understanding Parkinson’s Disease.- 16. Studies on the Toxicity of MPTP to Dopamine Neurons in Tissue and Cell Cultures.- 17. Toxicity of Structural Analogs of l-Methyl-4-phenyl Pyridinium (MPP+) and Related Compounds on Dopaminergic Neurons in Culture.- 18. Mechanisms of MPP+ Neurotoxicity: Oxyradical and Mihondrial Inhibition Hypotheses.- 19. Plasticity of Mesencephalic Dopaminergic Neurons.- 20. Trophic Effects of Striatal Proteins on Central Dopaminergic Neurons in Culture.- 21. Age-Related Changes of Dopaminergic Functions.- 22. Adrenal Medulla Transplants in Rodents and Nonhuman Primates: Regenerative Responses in the Host Brain.- 23. Preliminary Evaluation and Report on Human Adrenal Medullary Grafting.- 24. Behavioral Performance Improves after Fetal Substantia Nigra Transplant in Bonnet Monkeys with MPTP Induced Parkinsonism.- 25. Mechanisms of Action of Substantia Nigra and Adrenal Medulla Grafts.- 26. Recent Advances in Dopaminergic Implants.- 27. Reversal of Experimental Parkinsonism in African Green Monkeys Following Fetal Dopamine Neuron Transplantation.- 28. Transplantation of Human Dopaminergic Neurons in Parkinsonism: Experimental Reality and Future Clinical Feasibility.

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