Prostanoids and Drugs

Prostanoids and Drugs

by B. Samuelson (Editor)


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Product Details

ISBN-13: 9781468479409
Publisher: Springer US
Publication date: 05/09/2012
Series: Nato Science Series A: , #177
Edition description: 1989
Pages: 260
Product dimensions: 7.01(w) x 10.00(h) x 0.02(d)

Table of Contents

Molecular Biology of Leukotriene Formation.- Fundamental Mass Spectrometry and Eicosanoids Research.- Quantitative Analysis of Eicosanoids by Gas Chromatography Mass-Spectrometry.- Formation and Mechanism of Action of Epoxyeicosatrienoic Acids.- Reactive Eicosanoid Intermediates and Transcellular Biosynthesis.- Metabolism of Sulfidopeptide Leukotrienes.- Lipoxins: Biosynthesis, Metabolism and Physiological Functions.- Leukotrienes in the Lung and Cardiovascular System.- Blood Platelets, Aspirin and Prevention of Vascular Disease.- Cardioprotective Effects of Prostacyclin Analogues.- New Pharmacological Agents Which Antagonize Leukotriene D4 and Platelet Activating Factor.- 9?, 11?-Prostaglandin F2: a New Prostanoid, That Inhibits Platelet Aggregation and Constricts Blood Vessels.- Stenosis and Vascular Damage as an Experimental Model of Arterial Thrombosis: a Role for Prostanoids.- Renal and Platelet Eicosanoids in Chronic Glomerular Disease.- Role of Leukotrienes in Experimental Gastric Ulceration.- Role of Leukotrienes in Inflammatory Bowel Disease.- Gastric Cytoprotection.- Gastric Mucosal Damage by Nonsteroidal Anti-Inflammatory Drugs.- Aspects of Eicosanoids in Inflammation.- Modulation of the Inflammatory Potential of the 5-Lipoxygenase Pathway by Alternative Fatty Acids and Cytokines.- Inhibitors of Leukotriene Action: Potential Use in Asthma, Inflammatory Bowel Disease, and Cutaneous Inflammation.- Novel 5-Lipoxygenase Inhibitors in Inflammation and Asthma.- Eicosanoids as Regulators of Eicosanoid Release in Macrophages:Impact for Exacerbation of Tissue Damage by Non-Steroidal Anti-Inflammatory Drugs.- Eicosanoid Regulation of Macrophage-Mediated Anti-Tumor Function.- Interactions Between Anti-Inflammatory Drugs and Cancer Chemotherapy.

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