ISBN-10:
1860943179
ISBN-13:
9781860943171
Pub. Date:
06/28/2003
Publisher:
Imperial College Press
Protein Bioseparation Using Ultrafiltration: Theorypplications and New Developments

Protein Bioseparation Using Ultrafiltration: Theorypplications and New Developments

by Raja Ghosh

Hardcover

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Product Details

ISBN-13: 9781860943171
Publisher: Imperial College Press
Publication date: 06/28/2003
Pages: 188
Product dimensions: 5.98(w) x 9.26(h) x 0.60(d)

Table of Contents

Dedicationv
Prefacevii
Acknowledgementsix
List of Tablesxv
List of Figuresxvii
Chapter 1Protein Bioseparation: An Overview1
1.1Introduction1
1.2Proteins1
1.3Protein products2
1.4The requirement for protein bioseparation3
1.5Economic aspects of protein bioseparation5
1.6Protein bioseparation methods5
Chapter 2Ultrafiltration: An Overview13
2.1Introduction13
2.2Applications of ultrafiltration13
2.3Advantages of ultrafiltration15
Chapter 3Membranes19
3.1Introduction19
3.2Membrane material and chemistry19
3.3Membrane structure and morphology21
3.4Membrane preparation23
3.5Driving force in membrane separation processes24
3.6Membrane characterisation26
Chapter 4Membrane Module and Operation33
4.1Membrane elements and modules33
4.2Mode of operation44
Chapter 5Membrane Fouling47
5.1Introduction47
5.2Fouling mechanisms48
5.3Chemistry of adsorption51
5.4Initial and long-term fouling52
5.5Effect of concentration polarisation on fouling54
5.6Effect of permeate flux on fouling, and the critical flux concept54
5.7Effect of physicochemical parameters on fouling54
Chapter 6Permeate Flux in Ultrafiltration57
6.1Permeate flux57
6.2Enhancement of permeate flux63
6.3Fouling control68
Chapter 7Protein Transmission Through Ultrafiltration Membranes75
7.1Protein size75
7.2Protein transmission75
Chapter 8Selectivity of Protein Fractionation in Ultrafiltration87
8.1Selectivity87
8.2Enhancement of selectivity89
Chapter 9Protein Concentration91
9.1Introduction91
9.2Solute retention92
9.3Permeate flux and fouling in concentration processes94
9.4Modules95
9.5Mode of operation96
9.6Applications101
Chapter 10Diafiltration of Protein Solutions105
10.1Introduction105
10.2Permeate flux and fouling in diafiltration105
10.3Modules107
10.4Mode of operation108
10.5Applications108
Chapter 11Protein Clarification111
11.1Introduction111
11.2Protein transmission111
11.3Permeate flux and fouling in protein clarification112
11.4Particle transmission through UF membrane112
11.5Modules113
11.6Mode of operation114
11.7Applications118
Chapter 12Protein Fractionation121
12.1Introduction121
12.2Challenges facing ultrafiltration based protein fractionation121
12.3Selectivity enhancement123
12.4Thumb rules for protein fractionation133
12.5Application areas135
Chapter 13New Developments145
13.1New membranes145
13.2New membrane modules146
13.3Rapid process optimisation techniques147
13.4New modes of operation148
Appendix AGlossary of Membrane Terminology155
Appendix BList of Membrane Manufacturers163
Appendix CWebsites of Membrane Related Academic and Research Institutions165

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