Dylan Moor will do anything for freedom. Seven years ago, a gay plague spread to heterosexuals, killing millions and sparking brutal anti-gay riots. The guardians rounded up men who tested positive for the Homogene and imprisoned them in remote quarantine centres like desolate Camp Malheur. Since then, Dylan has hacked the camp's security systems and hoarded spare bits of electronics, seeking some way to escape. He has concluded the human guards are the only weakness in the facility's defences.
Camp guard Rafe Cowell is H-Negative. He figures the lust he feels watching prisoner 3218 masturbate on the surveillance cameras must be due to his loneliness and isolation. When he finally meets the young queer, he discovers that Dylan is brilliant, brave, sexy as hell - and claims to be in love with Rafe. Despite his qualms, Rafe find he can't resist the other man's charm. By the time Dylan asks for his help in escaping, Rafe cares too much for Dylan to refuse.
Dylan's plan goes awry and Rafe comes to his rescue. Soon they're both fugitives, fleeing from militant survivalists, murderous androids, homophobic ideologues and a powerful man who wants Dylan as his sexual toy. Hiding in the plague-ravaged city of Sanfran, Dylan and Rafe learn there's far more that their own safety at stake. Can they help prevent the deaths of millions more people? And can Rafe trust the love of a man who deliberately seduced him in order to escape from quarantine?