Recurrent Spontaneous Miscarriages

Recurrent Spontaneous Miscarriages

by Pankaj Desai M.D.

Paperback(3rd ed.)

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This second edition presents obstetricians and trainees up to date with the most recent developments and research associated with recurrent spontaneous miscarriages. Beginning with an introduction to the topic, the following sections discuss different aspects of the disorder including immunology, anatomy, genetics and ultrasonographic features of foetal demise. Causes of recurrent miscarriage are discussed including endocrinal problems and infections, and a brand new chapter is dedicated to endometriosis. The new edition includes clinical case studies and frequently asked questions, as well as 50 images, illustrations and tables. Key points New edition presenting latest developments in management of recurrent spontaneous miscarriages Includes many new topics including endometriosis and recurrent miscarriage Features clinical case studies and FAQs Previous edition published in 2009

Product Details

ISBN-13: 9789352702763
Publisher: Jp Medical Pub
Publication date: 04/30/2018
Edition description: 3rd ed.
Pages: 160
Product dimensions: 5.40(w) x 8.30(h) x 0.30(d)

About the Author

Pankaj Desai MD FICOG FICMCH is one of the best known academicians and educators in Obstetrics and Gynecology in India. All his eleven books published till date, have proved to be bestsellers, one of which was awarded the best book award, in the subject, in India. A prolific writer, he has contributed 39 chapters to different textbooks internationally and nationally. His outstanding academic contributions in the subject have been acknowledged and honored with 7 gold medals and 57 orations. An extremely popular teacher that he is, he has delivered 677 guest lectures in different parts of India and the world at the time of this book going for print. He has published 100 research papers in peer-reviewed journals till date, 9 of which have been awarded best research paper prizes. His website has become an extremely popular portal for students and practitioners of the subject seeking references and up-to-date knowledge. It has invited nearly 187000 hits by the time of this publication. His blogs on different academic and non-academic aspects being published on the net as Dr Pankaj Desai's blogs have also become very popular inviting more than 63000 reads as of now. His webinars conducted periodically on the net invite thousands of logins all throughout the world.

Table of Contents

1 Introduction to Recurrent Spontaneous Miscarriages-An Overview 1

Recurrent Spontaneous Miscarriages and Obstetric Vasculopathies 2

2 Ultrasonographic Features of Fetal Demise 4

Terminology 4

Gestational Sac Features 4

Subchorionic Hemorrhage 6

Fetal Cardiac Activity 9

Yolk Sac 14

Doppler Findings 16

3 Anatomical Causes of Recurrent Spontaneous Miscarriages 17

European Society of Human Reproduction and Embryology/European Society for Gynaecological Endoscopy Consensus on Diagnosis of Female Genital Anomalies 18

Congenital Uterine Anomalies 22

Acquired Uterine Anomalies 28

Cervical Incompetence 31

4 Immunology of Recurrent Pregnancy Miscarriage 42

Hyperhomocysteinemia and Recurrent Miscarriage 43

Systemic Lupus Erythematosus 44

Leads for Obstetric Vasculopathies through Recurrent Spontaneous Abortion 44

Fetus as an Allograft 44

Partner Specificity in Miscarriages 54

Autoimmunity in Recurrent Pregnancy Loss 56

The Miracle of Paradox 67

Laboratory Evaluation 68

Treatment 69

5 Genetics of Recurrent Miscarriages and Other Pregnancy Losses Sharad Gogate 77

Etiology 77

Blighted Ovum and Missed Abortion 81

Syndromes 84

Chromosomal Abnormalities and Fetal Malformations 84

Investigative Workup for Genetic Causes of Recurrent Pregnancy Loss 85

Genetic Counseling 90

Management 91

6 Eradocrinal Causes of Recurrent Spontaneous Miscarriages 94

Diabetes and Recurrent Spontaneous Miscarriages 95

Thyroid Abnormalities and Recurrent Spontaneous Miscarriages 95

Progesterone and Recurrent Spontaneous Miscarriages 96

Progesterone and Human Chorionic Gonadotropins Supplementation in the Treatment of Recurrent Spontaneous Miscarriages 98

Luteinizing Hormone Endocrinopathy and Recurrent Spontaneous Miscarriages 103

Polycystic Ovarian Syndrome-Insulin Resistance and Recurrent Pregnancy Loss 106

7 Endometriosis and Recurrent Spontaneous Miscarriages 115

Endometriosis and Pregnancy Loss-Examining the Evidence 115

Possible Causes of Endometriosis and Pregnancy Loss 117

8 Infections and Recurrent Spontaneous Miscarriages 121

Essentials of Laboratory Diagnosis for Proving the Association between Specific Organism and Recurrent Pregnancy Loss 123

Specific Infections and Recurrent Pregnancy Loss 124

9 Psychological Bearings of Recurrent Miscarriages 129

Immunology, Psychology and Recurrent Pregnancy Loss 130

Providing Psychological Support to Subjects with Recurrent Pregnancy Loss 131

Components of Support Giving that may be Helpful 132

10 Evidence-based Practice in Recurrent Spontaneous Miscarriages 135

Classification of Evidence Levels 135

Genetic Factors 137

Anatomical Factors 138

Cervical Weakness 139

Endocrinal Factors 139

Progesterone Supplementation 140

Human Chorionic Gonadotropin Supplementation 140

Immune Factors 141

Infections and Recurrent Spontaneous Abortion 142

Other Treatments 143

Allied Aspects 144

11 Approach to a Subject with Recurrent Spontaneous Miscarriages 148

The First Consultation 148

On Conception 152

Index 155

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