ISBN-10:
0982321953
ISBN-13:
9780982321959
Pub. Date:
01/11/2011
Publisher:
DiaMedica
The Remarkable Story of Copaxone

The Remarkable Story of Copaxone

by Kenneth P Johnson

Hardcover

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Product Details

ISBN-13: 9780982321959
Publisher: DiaMedica
Publication date: 01/11/2011
Pages: 256
Product dimensions: 6.10(w) x 9.10(h) x 1.00(d)

Table of Contents

Foreword ix

Preface xiii

Acknowledgments xvi

Part I Multiple Sclerosis: The Disease

1 What Is Multiple Sclerosis? 3

2 Multiple Sclerosis Heroes: Two Participants in Clinical Trials 23

3 The Central Nervous System 27

4 The Search for a Multiple Sclerosis Model 35

Part II The Weizmann Institute of Science

5 The Weizmann Institute of Science, Rehovot, Israel 45

6 Understanding Protein Structure and Function 53

7 Scientific Serendipity I 61

8 The 180-Degree Turn 69

9 Is It Effective, and Is It Safe? 77

10 Expanding Human Exposure 87

11 The Bornstein Trials 95

12 Could Cop 1 Be a Successful Drug? 107

Part III Teva Pharmaceuticals

13 Teva 115

14 The U.S. Pivotal Trial 123

15 From Anxiety to Euphoria 141

16 The Competition: Beta-Interferon 155

17 Challenges to Copaxone's Position as a First-line Multiple Sclerosis Treatment 163

18 Battles in the Marketplace 179

19 Unraveling the Mysteries of Copaxone 193

20 Becoming Number One 201

21 Multiple Sclerosis Heroes Revisited 211

22 Postscript 217

Index 219

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