Reviewer: Rahmat M. Talukder, PhD, RPh (West Coast University School of Pharmacy)
Description: This book presents the theoretical and practical aspects of common drug delivery systems.
Purpose: The objective is to present the concepts of pharmaceutics with relevance to clinical practice. An understanding of the formulation and processing factors that may affect the therapeutic outcomes of a drug product is critical in certain clinical decision making processes. In that respect, the objectives are relevant to patient care.
Audience: PharmD students are the intended audience, and the depth and breadth of most of the material is appropriate for them. The author is an educator.
Features: This book presents the scientific underpinnings of drug delivery systems in 18 chapters. The first several chapters deal with the physicochemical principles and their importance in designing a drug product. Solubility and related issues are well explained, and fundamental biopharmaceutical aspects pertinent to drug delivery systems are discussed. Subsequent chapters discuss drug delivery technologies based on the route of administration, e.g., oral, ocular, nasal, transdermal, etc. Many chapters include patient counseling tips, which should be helpful for students. Providing examples of marketed products based on the delivery technology discussed in the chapter makes the concept interesting and relevant. The key concepts of each chapter are presented separately in bullets and several questions and cases at the end of the chapter allow students to evaluate their understanding of the topic. Where applicable, chapters incorporate patient counseling tips. All of these features are helpful for students. There are a few shortcomings. One chapter covers novel drug delivery systems, but neither the depth nor the extent of the coverage seems adequate. Nanotechnology and biotechnology based drug delivery systems could have used further elaboration. Brief discussions of compendial methods of evaluation of each dosage form would have been appropriate, and a separate chapter on preformulation would help fulfill the objectives of the book. Finally, there are many typos.
Assessment: The fundamental theoretical and practical aspects of various drug delivery systems that this book presents will help students develop a solid understanding of the subject. It provides the conceptual basis of the science of dosage in a way that appears relevant to PharmD students. This book covers similar material that other pharmaceutics books do, but the examples of currently marketed products make this one more interesting to its target audience. Certain topics could have used further elaboration to improve clarity. The many typos will distract students.