Replicating Vaccines: A New Generation

Replicating Vaccines: A New Generation

Paperback(2011)

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Product Details

ISBN-13: 9783034803168
Publisher: Springer Basel
Publication date: 12/27/2012
Series: Birkhäuser Advances in Infectious Diseases
Edition description: 2011
Pages: 447
Product dimensions: 6.10(w) x 9.25(h) x 0.04(d)

Table of Contents

SECTION 1: Today’s Live Attenuated Vaccines.- Live Vaccines and their Role in Modern Vaccinology.- Live Attenuated Vaccines: Influenza, Rotavirus and Varicella Zoster.- Classical Live Viral Vaccines.- SECTION 2: Genetically Attenuated Micro-Organisms as Vaccines.- Recombinant Live Vaccines to Protect Against the Severe Acute Respiratory Syndrome Coronavirus.- Live Attenuated Shigella Vaccines. Is encouraging good enough?.- New generation BCG vaccines.- SECTION 3: Manipulating Host-Pathogen Interactions to Make Vaccines.- Basic Science Paves the Way to Novel Safe and Effective Pestivirus Vaccines.- Live Attenuated Influenza Virus Vaccines: NS1 Truncation as an Approach to Virus Attenuation Approaches.- An Attenuated Herpes implex Virus 1 Live Virus Vaccine Candidate that is Replication Competent but Defective in Epithelial Cell to Cell and Neuronal Spread.- RSV Deletion Mutant – Innate Immunity.- Live Attenuated Cholera Vaccines: Flagella and Reactogenicity.- SECTION 4: New Types of Replicating Vaccines.- Replication-defective Herpes simplex Virus Mutant Strains as Genital Herpes Vaccines and Vaccine Vectors.- Nucleic Acid-Based Infectious and Pseudo-Infectious Flavivirus Vaccines.- Application of Cleavage Activation Mutants of Influenza Virus as Live Vaccines.- Alphavirus Particle-based Vaccine Vectors.- Recombinant, Chimeric, Live, Attenuated Vaccines against Flaviviruses and Alphaviruses.

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