Retroviral Immunology: Immune Response and Restoration / Edition 1

Retroviral Immunology: Immune Response and Restoration / Edition 1

by Giuseppe Pantaleo
Pub. Date:
Springer-Verlag New York, LLC
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Retroviral Immunology: Immune Response and Restoration / Edition 1

Although there have been many books on HIV and AIDS, surprisingly little has been published that focuses on the immunology of retroviral infections in general, and HIV in particular. Retroviral Immunology: Immune Response and Restoration is the first book of its kind to address the most important aspects of the immunology of retroviruses, including not only the virus-specific immune responses, but also genetic and virologic factors modulating these responses. The book also deals directly with the emerging concept of immune restora­ tion in retroviral infections, a particularly important subject to the thousands of clinicians who deal with this problem on a daily basis. With the advent of highly effective antiviral drug regimens to slow down the replication of HIV and the progression of AIDS, new challenges and opportunities are arising. Restoration of general immune function has brought with it not only complica­ tions of immune restoration-mediated disease, but also the realistic hope for meaningful restoration of the ability to control HIV replication with the immune system. Leading scientists in the field have summarized the most current informa­ tion regarding experimental and clinical aspects of retroviral infections. Retroviral Immunology: Immune Response and Restoration should prove an impor­ tant point of reference for basic scientists and clinicians in this area of research. We are indebted to all of our authors for their excellent contributions.

Product Details

ISBN-13: 9780896036758
Publisher: Springer-Verlag New York, LLC
Publication date: 10/18/2007
Series: Infectious Disease Series
Edition description: 2001
Pages: 336
Product dimensions: 7.01(w) x 9.92(h) x 0.03(d)

Table of Contents

Epidemiological and Immunological Implications of the Global Variability of HIV-1
Bette T. Korber, Brian Foley, Brian Gaschen, and Carla Kuiken

Role of Chemokines and Their Receptors in the Pathogenesis of HIV Infection
Frederick S. Lee, Gabriele Kuschert, Otto O. Yang, and Andrew D. Luster

Cytokines and Chemokines in HIV Infection
Guido Poli

Development and Reconstitution of T-Lymphoid Immunity
Krishna V. Komanduri and Joseph M. McCune

HIV Gene Products as Manipulators of the Immune System
Aram Mangasarian and Didier Trono

Immune Response to Murine and Feline Retroviruses
Daniela Finke and Hans Acha-Orbea

Immune Response to HTLV-I and HTLV-II
Samantha S. Soldan and Steven Jacobson

HIV-Specific Neutralizing Antibodies
David C. Montefiori

Cytotoxic T-Cell Responses in Acute and Chronic HIV-1 Infection
Hugo Soudeyns and Giuseppe Pantaleo

Characterization of the HIV-1-Specific T-Helper Cell Response
Bruce D. Walker

Immune Responses to Nonhuman Primate Lentiviruses
Amitinder Kaur, Marie-Claire Gauduin, and R. Paul Johnson

Intrahost Selective Pressure and HIV-1 Heterogeneity During Progression to AIDS
Vladimir V. Lukashov and Jaap Goudsmit

Polymorphism in HLA and Other Elements of the Class I and II Response Pathways
Richard A. Kaslow and R. Pat Bucy

Immunologic Approaches to the Therapy of Patients with HIV Infection
H. Clifford Lane and Scott Seeley

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