This document provides guidance on how to conduct the offsite consequence analyses for Risk Management Programs required under the Clean Air Act (CAA). Section 112(r)(7) of the CAA directed the U.S. Environmental Protection Agency (EPA) to issue regulations requiring facilities with large quantities of very hazardous chemicals to prepare and implement programs to prevent the accidental release of those chemicals and to mitigate the consequences of any releases that do occur. This guidance document provides a simple methodology for conducting offsite consequence analyses. It provides generic reference tables of distances, applicable to most of the regulated toxic substances, and chemical-specific tables for ammonia, chlorine, and sulfur dioxide. This guidance also provides reference tables of distances for consequences of fires and explosions of flammable substances. In some cases, the rule allows users of this document to adopt generic assumptions rather than the site-specific data required if another model is employed.