Sequence Analysis Primer

Sequence Analysis Primer

Sequence Analysis Primer

Sequence Analysis Primer

Paperback(1991)

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Overview

Computerized sequence analysis is an integral part of biotechnological research, yet many biologists have received no formal training in this important technology. Sequence Analysis Primer offers the beginner the necessary background to enter this vital field and helps more seasoned researchers to fine-tune their approach. It covers basic data manipulation such as homology searches, stem-loop identification, and protein secondary structure prediction, and is compatible with most sequence analysis programs. A detailed example giving steps for characterizing a new gene sequence provides users with hands-on experience when combined with their current software. The book will be invaluable to researchers and students in molecular biology, genetics, biochemistry, microbiology, and biotechnology.

Product Details

ISBN-13: 9780333550922
Publisher: Palgrave Macmillan UK
Publication date: 06/01/1991
Series: UWBC Biotechnical Resource Series , #14326
Edition description: 1991
Pages: 279
Product dimensions: 5.98(w) x 9.02(h) x (d)

About the Author

National Cancer Institute

Genetics Computer Group, Inc.

Table of Contents

1. DNA, Peter M. Rice, Keith Elliston, and Michael Gribskov1.1. Sequencing Project Management1.2. Identification of Simple Sites and Transcriptional Signals1.3. Coding Region Identification1.4. RNA Structure1.5. DNA Structure1.6. Summary2. Protein, Roland Lüthy and David Eisenberg2.1. Physical Properties2.2. Structural Properties2.3. Summary3. Similarity and Homology, David J. States and Mark S. Boguski3.1. Similarity versus Homology3.2. Dot Matrix Methods3.3. Dynamic Programming Methods3.4. Scoring Systems3.5. Summary4. Practical Aspects: Analysis of Notch, Lisa Caballero4.1. cDNA Sequence Analysis4.2. Protein Analysis: Determining Structure and Function4.3. Genomic DNA4.4. Summary
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