Sickle Cell Disease and Hematopoietic Stem Cell Transplantation

Sickle Cell Disease and Hematopoietic Stem Cell Transplantation

Hardcover(1st ed. 2018)

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Product Details

ISBN-13: 9783319623276
Publisher: Springer International Publishing
Publication date: 09/21/2017
Edition description: 1st ed. 2018
Pages: 334
Product dimensions: 6.10(w) x 9.25(h) x (d)

About the Author


Emily Riehm Meier, MD, MSHS

Pediatric Hematologist and Director, Sickle Cell Research, Indiana Hemophilia and Thrombosis Center, Indianapolis, IN, USA


Allistair Abraham, MD
Children’s National Medical Center, Division of Blood and Marrow Transplantation, Washington, DC, USA


Ross M. Fasano, MD
Emory University School of Medicine, Department of Pathology & Laboratory Medicine, Atlanta GA, USA

Table of Contents

Part I Sickle Cell Disease

1. Clinical Manifestations of Sickle Cell Disease Across the Lifespan

Lydia H. Pecker, Jane Little

2. Pathobiology of Sickle Cell Disease Vaso-Occlusion and Targeted Therapies

Kerry A. Morrone, Jennifer Davila, W. Beau Mitchell, Deepa Manwani

3. Current Non-HSCT Related Treatments for SCD

Claire L. Anderson, Deepika S. Darbari

4. Risk Based Therapies for Sickle Cell Disease

Emily R. Meier

5. Transfusion Support of the Patient with Sickle Cell Disease Undergoing Transplantation

Jeanne E. Hendrickson, Ross M. Fasano

6. Neurological Manifestations of Sickle Cell Disease and Their Impact on Allogeneic Hematopoietic Stem Cell Transplantation

Jessica Carpenter, Monica L. Hulbert

Part II Hematopoietic Stem Cell Transplantation

7. Overview of Hematopoietic Stem Cell Transplantation for Non-Malignant Diseases

Karen L Zimowski, Shanmuganathan Chandrakasan

8. Unique Challenges of Hematopoietic Stem Cell Transplant for Sickle Cell Disease

Pooja Khandelwal, Michael Grimley

9. The Ethics of Hematopoietic Stem Cell Transplantation for Sickle Cell Disease

Robert Sheppard Nickel, Naynesh Kamani

10. Psychosocial Care and Education of Children with Sickle Cell Disease undergoing Hematopoietic Stem Cell Transplant and their Families

Steven J. Hardy, Jasmine Holt, Amanda L. Thompson

11. Long Term Effects of Hematopoietic Stem Cell Transplantation for Sickle Cell Disease

Karim T. Sadak, Angela R. Smith, Monica Bhatia

12. Matched Sibling Donor Hematopoietic Stem Cell Transplantation for Sickle Cell Disease

Gregory M.T. Guilcher, John T. Horan

13. Unrelated Donor Hematopoietic Stem Cell Transplantation for Sickle Cell Disease

Alexander Ngwube, Shalini Shenoy

14. Haploidentical Hematopoietic Cell Transplantation for Sickle Cell Disease

Elizabeth O. Stenger, Allistair Abraham

15. Gene Therapy 101: The Path Toward Becoming a Realistic Cure for Patients with Sickle Cell Disease

Alexis Leonard, Allistair Abraham

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