Signal Transduction in Leukocytes: G Protein-Related and Other Pathways / Edition 1 available in Hardcover
- Pub. Date:
- Taylor & Francis
Signal Transduction in Leukocytes presents important principles and various aspects of cellular regulation in leukocytes. The book discusses receptor structure and signaling, emphasizing cytokine receptors and the T cell and B cell antigen receptors. It investigates the role of the heterotrimeric G proteins and small G proteins as transducers.
Authorities in each field cover a wide range of topics. They explore propagation of signaling cascades through second messengers and serine/threonine kinases, the initiation of signaling from the B and T cell antigen receptors by tyrosine phosphorylation and protein recruitment, and the role of signaling in cell-cell interactions and the regulation of the cell cycle. The book outlines the relationship of receptor signaling to inflammatory reactions of neutrophils, eosinophils, and macrophages.
|Publisher:||Taylor & Francis|
|Edition description:||New Edition|
|Product dimensions:||6.40(w) x 9.30(h) x 1.10(d)|
Table of Contents
Overview of Signal Transduction in Leukocytes. Signal Transduction from Cytokine Receptors. Structure and Function of Receptor-Associated G Proteins. Role of Small GTP-Binding Proteins in Leukocyte Signal Transduction. Emerging Paradigms of Protein Phosphorylation in Mitogenic Signal Transduction. Regulation of src Family PTKs during T Cell Activation. The B Cell Antigen Receptor and Its Role in B Lymphocyte Regulation. Signal Transduction in the Human Neutrophil. Eosinophils: Receptors and Signal Transduction. Intracellular Signaling Pathways Regulating Inflammatory Gene Expression in Mononuclear Phagocytes. Appendix.