Signaling Pathways for Translation: Insulin and Nutrients

Signaling Pathways for Translation: Insulin and Nutrients

Paperback(Softcover reprint of the original 1st ed. 2001)

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Overview

Signaling Pathways for Translation: Insulin and Nutrients by Robert E. Rhoads

This book deals with anabolic mechanisms which regulate eukaryotic protein synthesis, with particular emphasis on insulin and amino acids. Six chapters written by leading experts in the field provide both new data and comprehensive literature reviews. The regulation of both the eIF2 and eIF4 groups of initiation factors by signal transduction mechanisms is presented, and translation is related to cellular growth in response to nutrient and hormonal signals.

Product Details

ISBN-13: 9783642625893
Publisher: Springer Berlin Heidelberg
Publication date: 10/30/2012
Series: Progress in Molecular and Subcellular Biology , #26
Edition description: Softcover reprint of the original 1st ed. 2001
Pages: 186
Product dimensions: 6.10(w) x 9.25(h) x 0.02(d)

Table of Contents

Insulin Signaling and the Control of PHAS-I Phosphorylation.- Insulin, Phorbol Ester and Serum Regulate the Elongation Phase of Protein Synthesis.- Regulation of Protein Synthesis by Insulin Through IRS-1.- Regulation of Eukaryotic Initiation Factor eIF2B.- The p70 S6 Kinase Integrates Nutrient and Growth Signals to Control Translational Capacity.- Regulation of Translation Initiation by Amino Acids in Eukaryotic Cells.

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