Single-cell Omics, Volume 2: Advances in Applications provides the latest single-cell omics applications in the field of biomedicine. The advent of omics technologies have enabled us to identify the differences between cell types and subpopulations at the level of the genome, proteome, transcriptome, epigenome, and in several other fields of omics. The book is divided into two sections: the first is dedicated to biomedical applications, such as cell diagnostics, non-invasive prenatal testing (NIPT), circulating tumor cells, breast cancer, gliomas, nervous systems and autoimmune disorders, and more. The second focuses on cell omics in plants, discussing micro algal and single cell omics, and more.
This book is a valuable source for bioinformaticians, molecular diagnostic researchers, clinicians and several members of biomedical field interested in understanding more about single-cell omics and its potential for research and diagnosis.
- Covers the diverse single cell omics applications in the biomedical field
- Summarizes the latest progress in single cell omics and discusses potential future developments for research and diagnosis
- Written by experts across the world, it brings different points-of-view and study cases to fully give a comprehensive overview of the topic
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About the Author
Vasco Azevedo is graduated from veterinary school of the Federal University of Bahia in 1986. He obtained his Master (1989) and Ph.D. (1993) degrees in microbial genetics from Institut National Agronomique Paris-Grignon (INAPG) and Institut National de la Recherche Agronomique (INRA), France, respectively. He did his Post-doctoral research (1994) at Department of Microbiology, School of Medicine, University of Pennsylvania. USA. Since 1995, he is a Professor at Federal University of Minas Gerais (UFMG), Brazil. In 2004, Prof. Azevedo won the Livre-docência contest at the University of São Paulo, which is considered the best university in Brazil. Livre-docência is a degree awarded by the Higher Education Department of Brazil through a public examination open only to the doctoral degree holders and is a recognition to a superior quality of teaching and research. In 2017, Prof. Azevedo defended his third thesis to become a Doctorate in Bioinformatics from the UFMG. He is a also a Fellow of Brazilian Academy of Sciences. He has published 380 research articles, 3 books, and 29 book chapters. Prof. Azevedo is expert in bacterial genetics, genomics, transcriptome, proteomics, and development of new vaccines and diagnostics against infectious diseases. He is pioneer in genetics of Lactic Acid Bacteria and Corynebacterium pseudotuberculosis in Brazil.
Table of Contents
Section I Single-Cell Omics: Biomedical Applications 1. Single-Cell Diagnostics, Prognosis, and Therapy 2. Single-Cell Omics in Noninvasive Prenatal Testing (NIPT) 3. Single-Cell Omics: Circulating Tumor Cells 4. Single-Cell Technology for Human Gliomas 5. Application of Single-Cell Omics in Breast Cancer 6. Single-Cell Omics: Strategies Towards Theranostic Biomarker Discovery Along the Continuum of Premalignant to Invasive Disease in Oncology 7. Single-Cell Omics in CVDs 8. Single-Cell Omics in Metabolic Disorders 9. Single-Cell Omics in Autoimmune Disorders 10. Single-Cell Omics in Human Reproductive Medicine-Our Clinical Experiences in Single-Cell Therapy 11. Single-Cell Omics for Drug Discovery and Development 12. Single-Cell Omics in Personalized Medicine 13. Cell-Based Medicine and Therapy
Section II Single-Cell Omics in Plants 14. Single-Cell Omics Approaches in Plants 15. Bulk to Individuality: Specifying Plants’ Cellular Functions Through Single-Cell Omics 16. Single-Cell-Type Metabolomics for Crop Improvement 17. Single-Cell Omics in Crop Plants: Opportunities and Challenges